SCHEMBL2342091

SCHEMBL2342091

Nc1ncnc2c1ncn2O

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 10/20 0.60
ADORA1 P30542 7/20 0.60
PI4KA P42356 7/20 0.55
PI4K2B Q8TCG2 7/20 0.55
PI4K2A Q9BTU6 7/20 0.55
PI4KB Q9UBF8 7/20 0.55
ADORA2B P29275 2/20 0.55
EGFR P00533 1/20 0.51
GSK3B P49841 1/20 0.51
AHCY P23526 5/20 0.50
ADORA3 P0DMS8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL580610 0.78 ADORA2A (0.64) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL28191737 0.77 ADORA2A (0.34) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL667204 0.77 ADORA2A (0.62) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL28413958 0.77 ADORA2A (0.62) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL25325575 0.75 ADORA2A (0.33) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL9074153 0.75 ADORA2A (0.60) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL13007709 0.75 ADORA2A (0.60) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL1357265 0.75 ADORA2A (0.60) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL11908593 0.75 ADORA2A (0.60) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL8069211 0.75 ADORA2A (0.60) ADORA2AADORA1PI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3922266-B1 TOLL-LIKE RECEPTOR 7 OR 8 AGONIST-CHOLESTEROL COMPLEX, AND USE OF SAME PROGENEER INC (KR) 2026-04-08 EP claimed
US-20230390406-A1 Star Polymer Drug Conjugates BARINTHUS BIOTHERAPEUTICS NORTH AMERICA, INC. 2023-12-07 US claimed
US-20230348903-A1 OLIGONUCLEOTIDES Hudson Institute of Medical Research (AU) 2023-11-02 US claimed
EP-4228701-A1 STAR POLYMER DRUG CONJUGATES Vaccitech North America, Inc. (US) 2023-08-23 EP claimed
WO-2023082821-A1 SERUM METABOLISM MARKER FOR DIAGNOSING BENIGN AND MALIGNANT PULMONARY NODULES AND USE THEREOF 上海市第一人民医院 2023-05-19 WO claimed
CN-115916978-A Oligonucleotides 哈德森医学研究所 2023-04-04 CN claimed
US-20230100429-A1 LIVE-PATHOGEN-MIMETIC NANOPARTICLES BASED ON PATHOGEN CELL WALL SKELETON, AND PRODUCTION METHOD THEREOF Progeneer Inc. (KR) 2023-03-30 US claimed
EP-4153751-A1 OLIGONUCLEOTIDES Hudson Institute of Medical Research (AU) 2023-03-29 EP claimed
CN-115666637-A Nano particle simulating live pathogen based on pathogen cell wall skeleton and preparation method thereof 蛋白科技先锋 2023-01-31 CN claimed
EP-4115901-A1 LIVE-PATHOGEN-MIMETIC NANOPARTICLES BASED ON PATHOGEN CELL WALL SKELETON, AND PRODUCTION METHOD THEREOF PROGENEER INC. (KR) 2023-01-11 EP claimed
US-20030119777-A1 Oligoribonucleotides and ribonucleases for cleaving RNA ISIS PHARMACEUTICALS, INC. 2003-06-26 US claimed
US-20030096784-A1 Oligoribonucleotides and ribonucleases for cleaving RNA ISIS PHARMACEUTICALS, INC. 2003-05-22 US claimed
US-20030096287-A1 Oligoribonucleotides and ribonucleases for cleaving RNA IONIS PHARMACEUTICALS, INC. 2003-05-22 US claimed
US-20030096286-A1 Oligoribonucleotides and ribonucleases for cleaving RNA ISIS PHARMACEUTICALS, INC. 2003-05-22 US claimed
US-20020165189-A1 Oligoribonucleotides and ribonucleases for cleaving RNA ISIS PHARMACEUTICALS, INC. 2002-11-07 US claimed
JP-2000510446-A 2000-08-15 JP claimed
EP-0928290-A4 OLIGORIBONUCLEOTIDES AND RIBONUCLEASES FOR CLEAVING RNA ISIS PHARMACEUTICALS INC (US) 2000-01-19 EP claimed
EP-0928290-A1 OLIGORIBONUCLEOTIDES AND RIBONUCLEASES FOR CLEAVING RNA ISIS PHARMACEUTICALS, INC. (US) 1999-07-14 EP claimed
US-5898031-A Oligoribonucleotides for cleaving RNA ISIS PHARMACEUTICALS, INC. (US) 1999-04-27 US claimed
WO-1997046570-A1 OLIGORIBONUCLEOTIDES AND RIBONUCLEASES FOR CLEAVING RNA ISIS PHARMACEUTICALS, INC. (US) 1997-12-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230100429-A1 LIVE-PATHOGEN-MIMETIC NANOPARTICLES BASED ON PATHOGEN CELL WALL SKELETON, AND PRODUCTION METHOD THEREOF TLR8, TLR7, TLR1 ADORA2A 2115/4885ADORA1 3330/4885PI4KA 513/4885
US-20230390406-A1 Star Polymer Drug Conjugates CCND3, CCND2, DRD3 ADORA2A 1265/4885ADORA1 661/4885PI4KA 1072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.