Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.41 |
| ▸ | KIF11 | P52732 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406097 | 0.81 | KCNN4 (0.46) | KCNN4KIF11HTR2AHTR2COPRK1 | |
| SCHEMBL2405440 | 0.79 | KCNN4 (0.44) | KCNN4KIF11HTR2AHTR2COPRK1 | |
| SCHEMBL30513670 | 0.69 | KMT2A (0.38) | HTR2AOPRK1KCNH2ADRA1ASMN1; SMN2 | |
| SCHEMBL2821675 | 0.69 | KMT2A (0.38) | HTR2AOPRK1KCNH2ADRA1ASMN1; SMN2 | |
| SCHEMBL16416723 | 0.69 | KCNN4 (0.45) | KCNN4KIF11HTR2AHTR2COPRK1 | |
| SCHEMBL27824023 | 0.67 | KCNN4 (0.53) | KCNN4KIF11HTR2AHTR2COPRK1 | |
| SCHEMBL1701240 | 0.66 | KCNN4 (0.53) | KCNN4KIF11HTR2AHTR2COPRK1 | |
| SCHEMBL5967507 | 0.66 | KCNN4 (0.49) | KCNN4KIF11HTR2AHTR2COPRK1 | |
| SCHEMBL15069851 | 0.66 | KIF11 (0.50) | KCNN4KIF11HTR2AHTR2COPRK1 | |
| SCHEMBL3238217 | 0.65 | ALDH1A1 (0.43) | ADRA1ASMN1; SMN2KDM4ELMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105759-A1 | Melanocortin receptor 4 (mc4) agonists and their uses | ELI LILLY AND COMPANY (US) | 2007-05-10 | — | — | US | disclosed |
| EP-1644023-A2 | MELANOCORTIN RECPTOR 4(MC4) AGONISTS AND THEIR USES | ELI LILLY AND COMPANY (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005000339-A2 | MELANOCORTIN RECEPTOR 4(MC4) AGONISTS AND THEIR USES | ELI LILLY AND COMPANY (US) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105759-A1 | Melanocortin receptor 4 (mc4) agonists and their uses | MC4R, MC3R, MC1R | KCNN4 685/4885KIF11 3801/4885HTR2A 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.