Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.42 |
| ▸ | S100A10 | P60903 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 4/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577331 | 1.00 | HSD17B10 (0.48) | HSD17B10CHRM3KDM4EALDH1A1MAPT | |
| SCHEMBL5577265 | 0.92 | ALDH1A1 (0.50) | HSD17B10CHRM3KDM4EALDH1A1MAPT | |
| SCHEMBL5577263 | 0.92 | ALDH1A1 (0.50) | HSD17B10CHRM3KDM4EALDH1A1MAPT | |
| SCHEMBL5577601 | 0.92 | KDM4E (0.48) | HSD17B10CHRM3KDM4EALDH1A1MAPT | |
| SCHEMBL5577600 | 0.92 | KDM4E (0.48) | HSD17B10CHRM3KDM4EALDH1A1MAPT | |
| SCHEMBL5577307 | 0.89 | ANXA2 (0.43) | HSD17B10KDM4EALDH1A1MAPTGLA | |
| SCHEMBL5577310 | 0.89 | ANXA2 (0.43) | HSD17B10KDM4EALDH1A1MAPTGLA | |
| SCHEMBL5577905 | 0.88 | ANXA2 (0.43) | HSD17B10KDM4EALDH1A1MAPTGLA | |
| SCHEMBL5577900 | 0.88 | ANXA2 (0.43) | HSD17B10KDM4EALDH1A1MAPTGLA | |
| SCHEMBL5577327 | 0.88 | DRD2 (0.47) | HSD17B10KDM4EALDH1A1MAPTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1616862-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | HLA-DRB1, MIF, HLA-C | HSD17B10 4005/4885CHRM3 2099/4885KDM4E 4213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.