Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PER2 | O15055 | 1/20 | 0.41 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.41 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577311 | 0.90 | MEN1 (0.46) | MEN1KMT2AACHEATM | |
| SCHEMBL5577775 | 0.89 | ALDH1A1 (0.47) | MEN1KMT2AACHEATMPER2 | |
| SCHEMBL5577258 | 0.89 | RECQL (0.54) | MEN1KMT2AACHEATMPER2 | |
| SCHEMBL5577364 | 0.88 | MEN1 (0.46) | MEN1KMT2AACHESIGMAR1 | |
| SCHEMBL5577266 | 0.86 | MEN1 (0.46) | MEN1KMT2AATMCCR3MAPK1 | |
| SCHEMBL5577289 | 0.85 | MEN1 (0.53) | MEN1KMT2AACHEATMMAPK1 | |
| SCHEMBL5577412 | 0.84 | ACHE (0.60) | MEN1KMT2AACHEATMCCR3 | |
| SCHEMBL5577801 | 0.84 | ACHE (0.52) | MEN1KMT2AACHEATMCCR3 | |
| SCHEMBL5577590 | 0.84 | MEN1 (0.41) | MEN1KMT2AACHEATMMAPK1 | |
| SCHEMBL5577270 | 0.84 | MEN1 (0.44) | MEN1KMT2AACHEATMSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1616862-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | HLA-DRB1, MIF, HLA-C | MEN1 748/4885KMT2A 3527/4885ACHE 1504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.