Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577694 | 0.95 | SIGMAR1 (0.51) | DRD3MEN1KMT2ASIGMAR1CHRM4 | |
| SCHEMBL5577644 | 0.88 | CCR3 (0.53) | DRD3MEN1KMT2ASIGMAR1CHRM4 | |
| SCHEMBL5577560 | 0.86 | HTR4 (0.53) | DRD3MEN1KMT2ACHRM4ATM | |
| SCHEMBL5577399 | 0.85 | SIGMAR1 (0.53) | KMT2ASIGMAR1CHRM4ALDH1A1 | |
| SCHEMBL5577726 | 0.83 | SIGMAR1 (0.51) | DRD3KMT2ASIGMAR1CHRM4PLA2G1B | |
| SCHEMBL5577858 | 0.83 | SIGMAR1 (0.56) | MEN1KMT2ASIGMAR1CHRM4ATM | |
| SCHEMBL5577767 | 0.83 | MAPK1 (0.62) | DRD3KMT2AALDH1A1DRD2DRD4 | |
| SCHEMBL5577515 | 0.83 | POLB (0.53) | DRD3MEN1KMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL5577906 | 0.82 | SIGMAR1 (0.48) | DRD3SIGMAR1ALDH1A1KLKB1 | |
| SCHEMBL5577342 | 0.82 | DRD4 (0.57) | SIGMAR1CHRM4DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1616862-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | HLA-DRB1, MIF, HLA-C | DRD3 4080/4885MEN1 748/4885KMT2A 3527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.