Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17291833 | 0.84 | DPP7 (0.44) | ALDH1A1RAB9ACHRM2KDM4EDPP7 | |
| SCHEMBL13889990 | 0.83 | RAB9A (0.58) | ALDH1A1TP53RAB9ACHRM2PKM | |
| SCHEMBL28674603 | 0.82 | POLB (0.51) | ALDH1A1SMN1; SMN2TP53RAB9APOLB | |
| SCHEMBL18574031 | 0.82 | CHRM2 (0.62) | ALDH1A1SMN1; SMN2TP53CYP3A4ALOX15 | |
| SCHEMBL121529 | 0.82 | CHRM2 (0.70) | ALDH1A1SMN1; SMN2CHRM2PKMKDM4E | |
| SCHEMBL21723340 | 0.81 | RAB9A (0.39) | ALDH1A1SMN1; SMN2TP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL9479560 | 0.80 | CHRM2 (0.68) | ALDH1A1SMN1; SMN2RAB9ACHRM2PKM | |
| Hydrochloric Acid SCHEMBL2147064 | 0.80 | CHRM2 (0.68) | ALDH1A1SMN1; SMN2RAB9ACHRM2PKM | |
| SCHEMBL25175588 | 0.80 | CHRM2 (0.60) | ALDH1A1SMN1; SMN2CHRM2KDM4EHDAC3 | |
| SCHEMBL31114280 | 0.80 | CHRM2 (0.60) | ALDH1A1SMN1; SMN2CHRM2KDM4EHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12465590-B2 | Oxalamido-substituted tricyclic inhibitors of hepatitis b virus | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2025-11-11 | — | — | US | disclosed |
| WO-2025081019-A1 | KIF MODULATOR COMPOUNDS AND METHODS OF USE | IAMBIC THERAPEUTICS, INC. (US) | 2025-04-17 | — | — | WO | disclosed |
| US-12091425-B2 | Compounds that inhibit MCL-1 protein | AMGEN INC. (US) | 2024-09-17 | — | — | US | disclosed |
| CN-117843571-A | Delta-lactam compound based on naphthalene skeleton and synthesis method and application thereof | 天津师范大学 | 2024-04-09 | — | — | CN | disclosed |
| EP-4261830-A1 | NOVEL PEPTIDOMIMETIC COMPOUND AND DESIGN | Oita University Institute of Advanced Medicine, Inc. (JP) | 2023-10-18 | — | — | EP | disclosed |
| US-20230322671-A1 | PYRROLINONE COMPOUND AND METHOD FOR PREPARING THE SAME | WUHAN JIANMIN DAPENG PHARMACEUTICAL CO., LTD. (CN) | 2023-10-12 | — | — | US | disclosed |
| CN-116615423-A | Novel peptidomimetic compounds and design | 株式会社大分大学先端医学研究所 | 2023-08-18 | — | — | CN | disclosed |
| US-20230052348-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC. (US) | 2023-02-16 | — | — | US | disclosed |
| US-20220241241-A1 | OXALAMIDO-SUBSTITUTED TRICYCLIC INHIBITORS OF HEPATITIS B VIRUS | ISTITUTO NAZIONALE DI GENETICA MOLECOLARE - INGM (IT) | 2022-08-04 | — | — | US | disclosed |
| WO-2022124341-A1 | NOVEL PEPTIDOMIMETIC COMPOUND AND DESIGN | 株式会社大分大学先端医学研究所 | 2022-06-16 | — | — | WO | disclosed |
| US-8940919-B2 | Compound, method for producing the same, and method for producing oseltamivir phosphate | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2015-01-27 | — | — | US | disclosed |
| US-20140046087-A1 | Compound, Method for Producing the Same, and Method for Producing Oseltamivir Phosphate | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2014-02-13 | — | — | US | disclosed |
| US-20140046087-A1 | Compound, Method for Producing the Same, and Method for Producing Oseltamivir Phosphate | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2014-02-13 | — | — | US | disclosed |
| EP-2684866-A1 | COMPOUND AND METHOD FOR PRODUCING SAME, AS WELL AS METHOD FOR PRODUCING OSELTAMIVIR PHOSPHATE | Microbial Chemistry Research Foundation (JP) | 2014-01-15 | — | — | EP | disclosed |
| US-20130217874-A1 | METHOD FOR MAKING MACROCYCLES | RIGEL PHARMACEUTICALS, INC. (US) | 2013-08-22 | — | — | US | disclosed |
| US-20130217874-A1 | METHOD FOR MAKING MACROCYCLES | RIGEL PHARMACEUTICALS, INC. (US) | 2013-08-22 | — | — | US | disclosed |
| WO-2012061408-A2 | METHOD FOR MAKING MACROCYCLES | RIGEL PHARMACEUTICALS. INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| US-20100120716-A1 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PHENOMIX CORPORATION (US) | 2010-05-13 | — | — | US | disclosed |
| US-20100120716-A1 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PHENOMIX CORPORATION (US) | 2010-05-13 | — | — | US | disclosed |
| WO-2008070733-A2 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PHENOMIX CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12465590-B2 | Oxalamido-substituted tricyclic inhibitors of hepatitis b virus | OAT, SLC10A1, OTC | ALDH1A1 1116/4885SMN1; SMN2 4849/4885TP53 792/4885 |
| US-20140046087-A1 | Compound, Method for Producing the Same, and Method for Producing Oseltamivir Phosphate | CYP2F1, CYP3A4, CYP2E1 | ALDH1A1 287/4885SMN1; SMN2 3628/4885TP53 2288/4885 |
| US-20130217874-A1 | METHOD FOR MAKING MACROCYCLES | EZR, SQLE, CBR3 | ALDH1A1 1812/4885SMN1; SMN2 2914/4885TP53 4117/4885 |
| US-20230322671-A1 | PYRROLINONE COMPOUND AND METHOD FOR PREPARING THE SAME | C1S, C5, SULT1A1 | ALDH1A1 706/4885SMN1; SMN2 2797/4885TP53 4001/4885 |
| US-20220241241-A1 | OXALAMIDO-SUBSTITUTED TRICYCLIC INHIBITORS OF HEPATITIS B VIRUS | OAT, OTC, SLC10A1 | ALDH1A1 1766/4885SMN1; SMN2 4870/4885TP53 492/4885 |
| US-20100120716-A1 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PREP, HPN, PEPD | ALDH1A1 2640/4885SMN1; SMN2 4040/4885TP53 1892/4885 |
| US-20230052348-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | MCL1, BCL9, BCL2L1 | ALDH1A1 1891/4885SMN1; SMN2 1807/4885TP53 32/4885 |
| US-12091425-B2 | Compounds that inhibit MCL-1 protein | MCL1, BCL9, BCL2L1 | ALDH1A1 1891/4885SMN1; SMN2 1807/4885TP53 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.