Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.53 |
| ▸ | DRD3 | P35462 | 9/20 | 0.53 |
| ▸ | DRD4 | P21917 | 7/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.52 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577844 | 0.85 | SCN10A (0.56) | SCN2ASCN10AMCHR1CYP2D6CHRM1 | |
| SCHEMBL5577320 | 0.85 | DRD2 (0.58) | DRD2DRD3DRD4SCN2ASCN10A | |
| SCHEMBL5577580 | 0.84 | MAPT (0.62) | DRD2DRD3DRD4MCHR1CYP2D6 | |
| SCHEMBL5577826 | 0.83 | MT-CO2 (0.49) | DRD2DRD3HTR2AHTR1A | |
| SCHEMBL5577719 | 0.82 | CHRM3 (0.55) | DRD2DRD3DRD4MCHR1CYP2D6 | |
| SCHEMBL5577645 | 0.81 | SCN10A (0.54) | SCN2ASCN10AMCHR1 | |
| SCHEMBL5577730 | 0.80 | CCR1 (0.48) | DRD2DRD3DRD4MCHR1 | |
| SCHEMBL5577657 | 0.80 | GNRHR (0.45) | DRD2DRD3DRD4SCN2ASCN10A | |
| SCHEMBL5577434 | 0.80 | MAPK1 (0.51) | DRD2DRD3DRD4 | |
| SCHEMBL5577433 | 0.80 | DRD2 (0.53) | DRD2DRD3DRD4HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1616862-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | HLA-DRB1, MIF, HLA-C | DRD2 4468/4885DRD3 4080/4885DRD4 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.