SCHEMBL557845

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30493145	0.76	PLAU (0.59)	PLAULMNASMN1; SMN2MAPK1POLB
	SCHEMBL29030141	0.76	PLAU (0.59)	PLAULMNASMN1; SMN2MAPK1POLB
	SCHEMBL19666544	0.71	MIF (0.37)	PLAUGABRPGABRDGABRA1GABRB1
	SCHEMBL1663686	0.69	APLNR (0.33)	PLAU
	SCHEMBL2931701	0.69	APLNR (0.43)	PLAULMNASMN1; SMN2GABRA1GABRB2
	SCHEMBL23705481	0.69	APLNR (0.33)	—
	SCHEMBL30042247	0.69	APLNR (0.33)	—
	SCHEMBL31571869	0.69	PLAU (0.52)	PLAULMNASMN1; SMN2CYP2C9TSHR
	SCHEMBL1457304	0.69	ALDH1A1 (0.39)	TSHRGABRA1GABRB2MEN1MAPT
	SCHEMBL9665894	0.67	PLAU (0.49)	PLAULMNASMN1; SMN2CYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.