SCHEMBL557857

SCHEMBL557857

COc1cc(N)ncn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylene Chloride SCHEMBL27807271 0.92 LOX (0.39)
SCHEMBL1478401 0.82 CYP2C19 (0.48)
SCHEMBL6386093 0.79 CYP2C19 (0.47)
SCHEMBL10188104 0.77 ALDH1A1 (0.39)
SCHEMBL29250306 0.77 CYP2C19 (0.46)
SCHEMBL11373823 0.77 PIK3CD (0.37)
SCHEMBL9779809 0.76
SCHEMBL19679370 0.76 CA2 (0.41)
SCHEMBL17591580 0.76 ASIC3 (0.38)
SCHEMBL19905341 0.74 ASIC3 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119662023-A Corrosion-resistant acid-base-resistant silicone rubber cable and molding preparation method thereof 重庆瑞普电气实业股份有限公司 2025-03-21 CN claimed
CN-115215806-B Synthesis method of sulfanilamide-6-methoxypyrimidine 江苏天和制药有限公司 2024-03-29 CN claimed
CN-115677599-A Method for preparing 4- (p-acetamido benzene sulfonamide) -6-methoxy pyrimidine 沈阳化工研究院有限公司 2023-02-03 CN claimed
CN-115215806-A Method for synthesizing sulfanilamide-6-methoxypyrimidine 江苏天和制药有限公司 2022-10-21 CN claimed
CN-108864708-A Anticorrosive cable material of a kind of acid and alkali-resistance and preparation method thereof 曹佳男 2018-11-23 CN claimed
CN-108276346-A A kind of phenyl ring14The preparation method of the sulfa antibiotics of C flag 南京大学 2018-07-13 CN claimed
CN-105294576-B A kind of preparation method of 6 methoxy pyrimidine sodium of sulfanilamide (SN) 和夏化学(太仓)有限公司 2018-04-13 CN claimed
CN-102516182-A Preparation method for 4-amino-6-alkoxyl pyrimidine compounds YWK CHEMICALS TAICANG CO LTD 2012-06-27 CN claimed
US-7683097-B2 Topoisomerase inhibitors Propharmacon Inc. (US) 2010-03-23 US claimed
US-20050026968-A1 Heterocyclic amides with anti-tuberculosis activity UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2005-02-03 US claimed
WO-2005007625-A2 HETEROCYCLIC AMIDES WITH ANTI-TUBERCULOSIS ACTIVITY THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2005-01-27 WO claimed
EP-1422218-A1 ANTIVIRAL AGENT SHIONOGI & CO., LTD. (JP) 2004-05-26 EP claimed
EP-4727944-A1 [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT Perha Pharmaceuticals (FR) 2026-04-22 EP disclosed
EP-4717312-A1 PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES USEFUL AS A MEDICAMENT Perha Pharmaceuticals (FR) 2026-04-01 EP disclosed
US-12534474-B2 Dihydrofuropyridine derivatives as rho-kinase inhibitors CHIESI FARMACEUTICI S.P.A. (IT) 2026-01-27 US disclosed
US-12473289-B2 Heterocyclic compounds as delta-5 desaturase inhibitors and methods of use AMGEN INC. (US) 2025-11-18 US disclosed
US-20020137755-A1 Tyrosine kinase inhibitors BILODEAU MARK T (US) 2002-09-26 US disclosed
WO-2002045652-A2 TYROSINE KINASE INHIBITORS MERCK & CO., INC. (US) 2002-06-13 WO disclosed
EP-0166609-A2 Aryl derivatives of heterobicyclic compounds THE WELLCOME FOUNDATION LIMITED (GB) 1986-01-02 EP disclosed
US-3948915-A 2-Halopyrimidine derivatives and a method for their preparation DAIICHI SEIYAKU, CO., LTD. (JA) 1976-04-06 US disclosed