Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 4/20 | 0.40 |
| ▸ | UBE2M | P61081 | 5/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 5/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5579007 | 0.96 | UBE2M (0.41) | HTR2ACCR5UBE2MDCUN1D1KDR | |
| SCHEMBL5579168 | 0.92 | KDR (0.43) | UBE2MDCUN1D1KDRBRAFABL1 | |
| SCHEMBL13861193 | 0.85 | KDR (0.42) | KDRBRAFABL1BCRAXL | |
| SCHEMBL4339311 | 0.85 | KDR (0.48) | KDRBRAFABL1BCR | |
| SCHEMBL4334120 | 0.84 | KDR (0.42) | HTR2ACCR5KDRBRAFABL1 | |
| SCHEMBL3552886 | 0.84 | KDR (0.41) | KDRBRAFABL1BCRAXL | |
| SCHEMBL13861265 | 0.82 | KDR (0.41) | KDRBRAFABL1BCRAXL | |
| SCHEMBL4326793 | 0.82 | KDR (0.41) | HTR2ACCR5KDRBRAFGCK | |
| SCHEMBL5579154 | 0.81 | GCK (0.48) | KDRBRAFGCKAXL | |
| SCHEMBL4329939 | 0.81 | KDR (0.45) | CCR5KDRBRAFLTA4HABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070270421-A1 | Novel pyridine Derivative and Pyrimidine Derivative (1) | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270421-A1 | Novel pyridine Derivative and Pyrimidine Derivative (1) | HGF, MET, FLT1 | HTR2A 3623/4885CCR5 453/4885UBE2M 4671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.