Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.56 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 6/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10090415 | 0.92 | LMNA (0.64) | LMNAACSL1ACSL6MAPTNPC1 | |
| SCHEMBL9870777 | 0.86 | LMNA (0.60) | LMNAACSL1ACSL6MAPTNPC1 | |
| SCHEMBL5390554 | 0.84 | LMNA (0.58) | LMNAACSL1ACSL6MAPTNPC1 | |
| SCHEMBL16806176 | 0.83 | LMNA (0.60) | LMNAACSL1ACSL6MAPTNPC1 | |
| SCHEMBL10090173 | 0.83 | LMNA (0.60) | LMNAACSL1ACSL6MAPTNPC1 | |
| SCHEMBL30748196 | 0.82 | XDH (0.67) | ACSL1ACSL6NPC1BCHEACHE | |
| SCHEMBL7812629 | 0.82 | ACSL1 (0.77) | LMNAACSL1ACSL6MAPTNPC1 | |
| SCHEMBL7405337 | 0.82 | ACSL1 (0.56) | LMNAACSL1ACSL6MAPTNPC1 | |
| SCHEMBL7397081 | 0.82 | ACSL1 (0.56) | LMNAACSL1ACSL6MAPTNPC1 | |
| SCHEMBL10090166 | 0.81 | LMNA (0.61) | LMNAACSL1ACSL6MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| EP-0708767-B1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES | ABBOTT LAB (US) | 2001-02-14 | — | — | EP | disclosed |
| EP-0708767-A4 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES | ABBOTT LAB (US) | 1996-10-02 | — | — | EP | disclosed |
| US-5541333-A | TETHERED HAPTEN INTERMEDIATES | ABBOTT LABORATORIES (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0708767-A1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES | ABBOTT LABORATORIES (US) | 1996-05-01 | — | — | EP | disclosed |
| US-5464746-A | Haptens, tracers, immunogens and antibodies for carbazole and dibenzofuran derivatives | ABBOTT LABORATORIES (US) | 1995-11-07 | — | — | US | disclosed |
| WO-1995003296-A1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES | ABBOTT LABORATORIES (US) | 1995-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | PPARG, NCOA4, PPARA | LMNA 4004/4885ACSL1 287/4885ACSL6 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.