Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | HPGD | P15428 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.45 |
| ▸ | CA9 | Q16790 | 7/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.45 |
| ▸ | CA12 | O43570 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23302557 | 0.76 | GAA (0.61) | GAAACHENPC1MGAMSI | |
| SCHEMBL14857485 | 0.76 | CYP2A6 (0.35) | ACHEKDM4EHSD17B10CYP3A4MAOA | |
| SCHEMBL5579339 | 0.74 | GAA (0.46) | GAAACHENPC1MGAMSI | |
| SCHEMBL3277376 | 0.71 | GAA (0.49) | GAAACHENPC1MGAMSI | |
| SCHEMBL24788182 | 0.71 | CA9 (0.47) | GAAACHENPC1MGAMSI | |
| SCHEMBL30536506 | 0.71 | MEN1 (0.36) | MEN1KMT2APOLB | |
| SCHEMBL19038906 | 0.71 | MEN1 (0.36) | MEN1KMT2APOLB | |
| SCHEMBL28994323 | 0.70 | ALDH1A1 (0.59) | GAAACHENPC1MGAMSI | |
| SCHEMBL4740620 | 0.70 | GAA (0.48) | GAAACHENPC1MGAMSI | |
| Ayapin SCHEMBL6694210 | 0.69 | KDM4E (0.57) | GAAACHENPC1MGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929711-A | Use of novel compounds for preventing, ameliorating or treating amyotrophic lateral sclerosis | PRG科技株式会社 | 2022-08-19 | — | — | CN | claimed |
| US-20220402930-A1 | USE OF NOVEL COMPOUND, FOR PREVENTING, IMPROVING OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | PRG S&TECH INC. (KR) | 2022-12-22 | — | — | US | disclosed |
| EP-4056573-A1 | USE OF NOVEL COMPOUND, FOR PREVENTING, IMPROVING OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | PRG S&Tech Inc. (KR) | 2022-09-14 | — | — | EP | disclosed |
| CN-114929711-A | Use of novel compounds for preventing, ameliorating or treating amyotrophic lateral sclerosis | PRG科技株式会社 | 2022-08-19 | — | — | CN | disclosed |
| WO-2021086101-A1 | USE OF NOVEL COMPOUND, FOR PREVENTING, IMPROVING OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | (주)피알지에스앤텍 | 2021-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402930-A1 | USE OF NOVEL COMPOUND, FOR PREVENTING, IMPROVING OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | SOD1, SLC75A1, SLC43A1 | GAA 1104/4885ACHE 1595/4885NPC1 1151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.