Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4215184 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTTSHRMEN1 | |
| SCHEMBL16771555 | 0.82 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDBCAT2LMNA | |
| SCHEMBL4347119 | 0.81 | MAPT (0.42) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL162322 | 0.79 | MAPT (0.52) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL6555382 | 0.79 | MAPT (0.52) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL8729973 | 0.78 | ALDH1A1 (0.63) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL20581696 | 0.78 | MAPT (0.50) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| Hydrochloric Acid SCHEMBL27779824 | 0.78 | MAPT (0.50) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| Hydrochloric Acid SCHEMBL11603537 | 0.78 | MAPT (0.50) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| Hydrochloric Acid SCHEMBL393289 | 0.78 | MAPT (0.50) | ALDH1A1KDM4EMAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | disclosed |