Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.84 |
| ▸ | HPGD | P15428 | 3/20 | 0.84 |
| ▸ | GFER | P55789 | 1/20 | 0.84 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HBB | P68871 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666530 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HPGDGFERHSD17B10GAA | |
| SCHEMBL22203774 | 0.79 | ALDH1A1 (0.57) | ALDH1A1HPGDGFERALOX15HSD17B10 | |
| SCHEMBL5445305 | 0.79 | ALDH1A1 (0.57) | ALDH1A1HPGDGFERALOX15HSD17B10 | |
| SCHEMBL1006897 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HPGDGFERALOX15HSD17B10 | |
| SCHEMBL12573230 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HPGDGFERALOX15HSD17B10 | |
| SCHEMBL1006898 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HPGDGFERALOX15HSD17B10 | |
| SCHEMBL6025280 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HPGDGFERALOX15HSD17B10 | |
| SCHEMBL10523673 | 0.74 | ALDH1A1 (0.72) | ALDH1A1HPGDGFERALOX15HSD17B10 | |
| SCHEMBL2326261 | 0.74 | ALDH1A1 (0.65) | ALDH1A1HPGDGFERALOX15HSD17B10 | |
| SCHEMBL9019258 | 0.73 | ALDH1A1 (0.65) | ALDH1A1HPGDGFERALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |