SCHEMBL9019258

SCHEMBL9019258

CN(C)c1ccc(C(=Nc2ccccc2)c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
HPGD P15428 3/20 0.65
GFER P55789 1/20 0.65
ESR1 P03372 2/20 0.60
ESR2 Q92731 2/20 0.60
MAPK1 P28482 3/20 0.57
TSHR P16473 2/20 0.57
HSD17B10 Q99714 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
RAB9A P51151 3/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
NPC1 O15118 3/20 0.53
ADRA2A P08913 3/20 0.50
ADRA2B P18089 2/20 0.50
ADRA2C P18825 2/20 0.50
KDM4E B2RXH2 3/20 0.49
GLA P06280 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12352175 0.82 ESR2 (0.62) ALDH1A1HPGDGFERESR1ESR2
SCHEMBL12352176 0.82 ESR2 (0.62) ALDH1A1HPGDGFERESR1ESR2
SCHEMBL12336908 0.81 ESR2 (0.78) ESR1ESR2MEN1KMT2ANOS1
SCHEMBL19774411 0.81 ESR2 (0.60) ALDH1A1HPGDGFERESR1ESR2
SCHEMBL4450591 0.79 ESR2 (0.74) ALDH1A1ESR1ESR2MEN1KMT2A
SCHEMBL16234062 0.78 ESR2 (0.57) ALDH1A1HPGDGFERESR1ESR2
SCHEMBL16234038 0.78 ESR2 (0.57) ALDH1A1HPGDGFERESR1ESR2
SCHEMBL14607909 0.78 ALDH1A1 (0.56) ALDH1A1HPGDGFERESR1ESR2
SCHEMBL4403121 0.78 ESR2 (0.68) ALDH1A1ESR1ESR2RAB9AMEN1
SCHEMBL8087997 0.77 ALDH1A1 (0.70) ALDH1A1HPGDGFERMAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8003127-A None JP disclosed
JP-H083127-A PHENYLIMINE AND RECORDING MATERIAL USING THE SAME YAMADA CHEM CO LTD 1996-01-09 JP disclosed