SCHEMBL6025280

SCHEMBL6025280

CCN(CC)c1ccc(C(=NO)c2ccc(N(CC)CC)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.53
GAA P10253 3/20 0.53
KDM4E B2RXH2 3/20 0.53
HPGD P15428 3/20 0.53
GFER P55789 2/20 0.53
L3MBTL1 Q9Y468 3/20 0.48
TSHR P16473 3/20 0.48
CYP3A4 P08684 2/20 0.48
MAPK1 P28482 2/20 0.48
RECQL P46063 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
PSMD14 O00487 1/20 0.48
MAPT P10636 6/20 0.46
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
POLB P06746 3/20 0.46
NOX1 Q9Y5S8 2/20 0.46
MCL1 Q07820 1/20 0.46
ALDH3A1 P30838 1/20 0.45
ALDH1A3 P47895 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14221026 0.83 MAPT (0.50) ALDH1A1GAAKDM4EHPGDGFER
SCHEMBL216089 0.79 MAPT (0.46) ALDH1A1GAAKDM4EHPGDGFER
SCHEMBL9915626 0.78 ALDH1A1 (0.56) ALDH1A1GAAKDM4EHPGDGFER
SCHEMBL1735497 0.76 ALDH1A1 (0.74) ALDH1A1GAAKDM4EHPGDGFER
SCHEMBL14142582 0.76 GAA (0.44) ALDH1A1GAAKDM4EGFERL3MBTL1
SCHEMBL5579647 0.76 ALDH1A1 (0.84) ALDH1A1GAAKDM4EHPGDGFER
SCHEMBL213048 0.74 ALDH1A1 (0.41) ALDH1A1GAAKDM4EHPGDGFER
SCHEMBL216485 0.74 ALDH1A1 (0.41) ALDH1A1GAAKDM4EHPGDGFER
SCHEMBL1306139 0.74 MAPT (0.58) ALDH1A1GAAKDM4EGFERL3MBTL1
SCHEMBL1458445 0.74 ALDH1A1 (0.52) ALDH1A1GAAKDM4EHPGDGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1163553-B1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2006-06-14 EP disclosed
EP-1635220-A2 Oxime derivatives and the use thereof as photoinitiators Ciba Specialty Chemicals Holding Inc. (CH) 2006-03-15 EP disclosed
US-6806024-B1 MIXTURES OF ADDITION POLYMERS AND ACTIVATORS COMPRISING NITROGEN COMPOUNDS, USED AS SUBSTRATE COATINGS FOR COLOR FILTERS CIBA SPECIALTY CHEMICALS CORPORATION 2004-10-19 US disclosed
EP-1163553-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS Ciba SC Holding AG (CH) 2001-12-19 EP disclosed
WO-2000052530-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-09-08 WO disclosed