Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrolidine SCHEMBL3126591 | 0.97 | ALDH1A1 (0.42) | ALDH1A1CXCR4SMN1; SMN2 | |
| Pyrrolidine SCHEMBL28164931 | 0.95 | ALDH1A1 (0.40) | ALDH1A1CXCR4SMN1; SMN2 | |
| Piperidine SCHEMBL6426026 | 0.87 | ALDH1A1 (0.45) | ALDH1A1CXCR4SMN1; SMN2 | |
| Piperazine SCHEMBL27467104 | 0.86 | HIF1A (0.38) | CXCR4SMN1; SMN2 | |
| Pyrrolidine SCHEMBL8155017 | 0.84 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL17244 | 0.83 | — | — | |
| SCHEMBL14876768 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL122329 | 0.80 | — | — | |
| SCHEMBL28825030 | 0.80 | — | — | |
| Bromide SCHEMBL10701347 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070161591-A1 | Methods and compositions for treating neurological disease | UNIVERSITY OF MASSACHUSETTS (US) | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161591-A1 | Methods and compositions for treating neurological disease | SMN1; SMN2, CLN6, INA | ALDH1A1 2103/4885CXCR4 2049/4885SMN1; SMN2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.