Pyrrolidine

Pyrrolidine

SCHEMBL3126591

C1=CNCC1.C1CCNC1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
CXCR4 P61073 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperidine SCHEMBL5579726 0.97 ALDH1A1 (0.47) ALDH1A1CXCR4SMN1; SMN2
Pyrrolidine SCHEMBL28164931 0.97 ALDH1A1 (0.40) ALDH1A1CXCR4SMN1; SMN2
Piperazine SCHEMBL27467104 0.88 HIF1A (0.38) CXCR4SMN1; SMN2
Pyrrolidine SCHEMBL8155017 0.87 ALDH1A1 (0.32) ALDH1A1
SCHEMBL17244 0.85
SCHEMBL14876768 0.85
Piperidine SCHEMBL6426026 0.84 ALDH1A1 (0.45) ALDH1A1CXCR4SMN1; SMN2
Bromide SCHEMBL10701347 0.82
SCHEMBL5899334 0.82
Fluoride SCHEMBL923328 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100135942-A1 Depigmenting keratin materials utilizing dithiolane compounds L'OREAL (FR) 2010-06-03 US claimed
CN-114560828-B Polymerizable compound and optically anisotropic body formed therefrom 江苏创拓新材料有限公司 2024-01-26 CN disclosed
CN-113861128-B Polymerizable compound and optically anisotropic body 江苏创拓新材料有限公司 2023-08-01 CN disclosed
CN-114685540-A Polyoxy boron trifluoride salt electrolyte and preparation method and application thereof 北京卫蓝新能源科技有限公司 2022-07-01 CN disclosed
CN-114649572-A Sulfur-based boron trifluoride salt-containing electrolyte and preparation method and application thereof 北京卫蓝新能源科技有限公司 2022-06-21 CN disclosed
CN-114649585-A Polycyclic sulfur-based electrolyte and preparation method and application thereof 北京卫蓝新能源科技有限公司 2022-06-21 CN disclosed
CN-114649571-A Ternary sulfenyl boron trifluoride salt electrolyte and preparation method and application thereof 北京卫蓝新能源科技有限公司 2022-06-21 CN disclosed
CN-114649576-A Electrolyte containing bicyclic sulfur-based salt and preparation method and application thereof 北京卫蓝新能源科技有限公司 2022-06-21 CN disclosed
CN-114605442-A Multi-sulfur-based boron trifluoride salt electrolyte and preparation method and application thereof 北京卫蓝新能源科技有限公司 2022-06-10 CN disclosed
CN-114573616-A Ternary electrolyte containing bicyclic salt and preparation method and application thereof 北京卫蓝新能源科技有限公司 2022-06-03 CN disclosed
CN-107615556-A Electrolyte and metal hydride battery 巴斯夫公司 2018-01-19 CN disclosed
CN-107004912-A Electrolyte and metal hydride battery 巴斯夫公司 2017-08-01 CN disclosed
WO-2017070026-A1 CORROSION INHIBITION SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2017-04-27 WO disclosed
CN-103411892-B Analysis sample injection apparatus and method for making element form volatile by using organic matter cracking UNIV TIANJIN NORMAL 2015-03-25 CN disclosed
CN-103411892-A Analysis sample injection apparatus and method for making element form volatile by using organic matter cracking UNIV TIANJIN NORMAL 2013-11-27 CN disclosed
EP-1594438-A2 USE OF AN INHIBITOR OF 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE IN ORDER TO STIMULATE PIGMENTATION OF THE SKIN OR SKIN APPENDAGES L'OREAL (FR) 2005-11-16 EP disclosed
WO-2004073594-A2 USE OF AN INHIBITOR OF 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE IN ORDER TO STIMULATE PIGMENTATION OF THE SKIN OR SKIN APPENDAGES L'OREAL (FR) 2004-09-02 WO disclosed
US-6376484-B1 FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE ONO PHARMACEUTICAL CO., LTD. (JP) 2002-04-23 US disclosed
US-6136834-A TETRAZOLE PEPTIDES ONO PHARMACEUTICAL CO., LTD. (JP) 2000-10-24 US disclosed
US-4851322-A CYCLOHEPTA/B/PYRROLE DYES FUJI PHOTO FILM CO., LTD. (JP) 1989-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100135942-A1 Depigmenting keratin materials utilizing dithiolane compounds KRT18, NR1D1, RER1 ALDH1A1 994/4885CXCR4 4309/4885SMN1; SMN2 4718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.