Pyrrolidine

Pyrrolidine

SCHEMBL8155017

C1=CNCC1.C1CCNC1.c1cc[nH]c1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrrolidine SCHEMBL3126591 0.87 ALDH1A1 (0.42) ALDH1A1
Piperidine SCHEMBL5579726 0.84 ALDH1A1 (0.47) ALDH1A1
Pyrrolidine SCHEMBL28164931 0.84 ALDH1A1 (0.40) ALDH1A1
Pyrrolidine SCHEMBL4604231 0.79 ALDH1A1 (0.50) ALDH1A1
Piperidine SCHEMBL1583028 0.77 ALDH1A1 (0.56) ALDH1A1
Pyrrolidine SCHEMBL28317841 0.77 ALDH1A1 (0.47) ALDH1A1
Piperazine SCHEMBL27467104 0.77 HIF1A (0.38)
Piperidine SCHEMBL1288276 0.74 ALDH1A1 (0.53) ALDH1A1
Benzene SCHEMBL29096572 0.74
Pyrrole SCHEMBL6427563 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6162928-A CATALYTIC DEHYDROGENATION OF (SUBSTITUTED) PYRROLIDINE TO PYRROLES USING AS CATALYST PALLADIUM ON OXIDES OF RARE EARTH OR GROUP 4 METALS, OR PLATINUM AND PALLADIUM ON OXIDES OF ALUMINUM, RARE EARTH OR GROUP 4 METALS, AND 1A OR 2A OXIDES BASF AKTIENGESELLSCHAFT (DE) 2000-12-19 US disclosed