Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 2/20 | 0.31 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5118902 | 0.69 | BACE1 (0.30) | CTSDBACE1 | |
| SCHEMBL5579545 | 0.69 | BACE1 (0.32) | CTSDBACE1 | |
| SCHEMBL5579540 | 0.67 | BACE1 (0.33) | CTSDBACE1 | |
| SCHEMBL5579770 | 0.66 | BACE1 (0.32) | CTSDBACE1 | |
| SCHEMBL5579788 | 0.65 | HTT (0.34) | BACE1 | |
| SCHEMBL5579814 | 0.63 | BACE1 (0.33) | CTSDBACE1 | |
| SCHEMBL13181461 | 0.53 | SPHK2 (0.52) | — | |
| SCHEMBL27812754 | 0.52 | ALDH1A1 (0.43) | — | |
| SCHEMBL6647479 | 0.52 | BACE1 (0.46) | CTSDBACE1 | |
| SCHEMBL6170397 | 0.52 | BACE1 (0.41) | CTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294642-B2 | 1,3-Diamino-2-hydroxypropane pro-drug derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2007-11-13 | — | — | US | claimed |