⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35686 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL3104649 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL27488879 | 0.95 | HTT (0.38) | — | |
| SCHEMBL6731744 | 0.95 | — | — | |
| Iodide SCHEMBL3681300 | 0.95 | — | — | |
| SCHEMBL4070674 | 0.88 | LMNA (0.30) | — | |
| Guanidine SCHEMBL28319252 | 0.88 | LMNA (0.43) | — | |
| Deuterium Oxide SCHEMBL15813404 | 0.84 | — | — | |
| Bicarbonate SCHEMBL455147 | 0.84 | ALDH1A1 (0.39) | — | |
| SCHEMBL14868258 | 0.82 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235670-B2 | Photogenerated reagents | Gao, Xiaolian | 2007-06-26 | — | — | US | claimed |
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | claimed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | claimed |
| US-4695617-A | ALKENYLOXYSILANE, GUANIDINE-SUBSTITUTED SILICON COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1987-09-22 | — | — | US | claimed |
| US-20240228555-A9 | ANTIMICROBIAL PEPTIDOMIMETICS | BASILEA PHARMACEUTICA INTERNATIONAL AG, ALLSCHWIL (CH) | 2024-07-11 | — | — | US | disclosed |
| EP-4380689-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | Basilea Pharmaceutica International AG, Allschwil (CH) | 2024-06-12 | — | — | EP | disclosed |
| US-20240132553-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | SPEXIS AG (CH) | 2024-04-25 | — | — | US | disclosed |
| US-20230295234-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | SPEXIS AG (CH) | 2023-09-21 | — | — | US | disclosed |
| WO-2023012319-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | SPEXIS AG (CH) | 2023-02-09 | — | — | WO | disclosed |
| US-20220002344-A1 | NEW FUSION PEPTIDES AS ANTIMICROBIAL AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2022-01-06 | — | — | US | disclosed |
| EP-3911664-A1 | NEW FUSION PEPTIDES AS ANTIMICROBIAL AGENTS | Centre national de la recherche scientifique (FR) | 2021-11-24 | — | — | EP | disclosed |
| CN-111699546-A | Water-repellent protective film forming agent, chemical solution for forming water-repellent protective film, and method for surface treatment of wafer | 中央硝子株式会社 | 2020-09-22 | — | — | CN | disclosed |
| EP-0685457-A1 | GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1995-12-06 | — | — | EP | disclosed |
| EP-0685234-A1 | DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1995-12-06 | — | — | EP | disclosed |
| US-5373008-A | Phenylamidine and phenylguanidine derivatives and their use as anti-diabetic agents | THE BOOTS COMPANT PLC. (GB) | 1994-12-13 | — | — | US | disclosed |
| US-5223498-A | Hypoglycemic agents | THE BOOTS COMPANY PLC (GB) | 1993-06-29 | — | — | US | disclosed |
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | disclosed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | disclosed |
| US-4734479-A | Room temperature-curable organopolysiloxane composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |
| US-4721766-A | Room temperature-curable organopolysiloxane composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-01-26 | — | — | US | disclosed |