Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | APEX1 | P27695 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083564 | 0.89 | HSD17B10 (0.51) | ALDH1A1HPGDHSD17B10CYP1A2L3MBTL1 | |
| SCHEMBL11083559 | 0.85 | ALDH1A1 (0.52) | ALDH1A1HPGDHSD17B10CYP1A2L3MBTL1 | |
| SCHEMBL11082445 | 0.84 | HTT (0.70) | ALDH1A1HPGDHSD17B10CYP1A2L3MBTL1 | |
| SCHEMBL20118962 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HPGDHSD17B10CYP1A2L3MBTL1 | |
| SCHEMBL10546592 | 0.81 | L3MBTL1 (0.71) | ALDH1A1HSD17B10L3MBTL1HTTKDM4E | |
| SCHEMBL11088115 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10CYP1A2HTT | |
| SCHEMBL8079249 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HPGDHSD17B10CYP1A2L3MBTL1 | |
| SCHEMBL11079506 | 0.76 | KDM4E (0.55) | ALDH1A1HPGDHSD17B10CYP1A2L3MBTL1 | |
| SCHEMBL6547890 | 0.76 | ALDH1A1 (0.49) | ALDH1A1HPGDHSD17B10CYP1A2L3MBTL1 | |
| SCHEMBL11780045 | 0.76 | L3MBTL1 (0.65) | ALDH1A1HPGDHSD17B10CYP1A2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294642-B2 | 1,3-Diamino-2-hydroxypropane pro-drug derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2007-11-13 | — | — | US | claimed |
| JP-56152470-A | — | — | None | — | — | JP | disclosed |
| US-7348296-B2 | Binders for use in the thermosensitive elements of substantially light-insensitive thermographic recording materials | AGFA HEALTHCARE (BE) | 2008-03-25 | — | — | US | disclosed |
| US-7348296-B2 | Binders for use in the thermosensitive elements of substantially light-insensitive thermographic recording materials | AGFA HEALTHCARE (BE) | 2008-03-25 | — | — | US | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-4447618-A | PLANT GROWTH REGULATOR FOR LEGUMES | MONSANTO COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4422865-A | HERBICIDES AND PLANT GROWTH REGULANTS | MONSANTO COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| US-4362547-A | HERBICIDES; PLANT GROWTH REGULATORS | MONSANTO COMPANY (US) | 1982-12-07 | — | — | US | disclosed |
| JP-S56152470-A | PRODUCTION OF 2-BENZOTHIAZOLINONE DERIVATIVE | OTA SEIYAKU KK | 1981-11-26 | — | — | JP | disclosed |
| US-4289886-A | HERBICIDES, PLANT GROWTH REGULATORS | MONSANTO COMPANY (US) | 1981-09-15 | — | — | US | disclosed |