SCHEMBL6547890

SCHEMBL6547890

OCCn1c(=S)sc2ccccc21

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.49
CYP1A2 P05177 1/20 0.49
HPGD P15428 1/20 0.49
HSD17B10 Q99714 1/20 0.49
DRD2 P14416 1/20 0.48
SLC6A4 P31645 1/20 0.48
SLC6A3 Q01959 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.44
HTT P42858 1/20 0.44
KDM4E B2RXH2 1/20 0.40
PKM P14618 1/20 0.40
NPC1 O15118 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDO2 P48775 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14136137 0.90 DRD2 (0.52) ALDH1A1CYP1A2HPGDHSD17B10DRD2
SCHEMBL8079249 0.85 ALDH1A1 (0.51) ALDH1A1CYP1A2HPGDHSD17B10DRD2
SCHEMBL11782096 0.82 DRD2 (0.48) ALDH1A1CYP1A2HPGDHSD17B10DRD2
SCHEMBL11082445 0.80 HTT (0.70) ALDH1A1CYP1A2HPGDHSD17B10DRD2
SCHEMBL8030664 0.79 DRD2 (0.52) ALDH1A1CYP1A2HPGDHSD17B10DRD2
SCHEMBL11079506 0.79 KDM4E (0.55) ALDH1A1CYP1A2HPGDHSD17B10DRD2
SCHEMBL4614755 0.79 L3MBTL1 (0.69) ALDH1A1CYP1A2L3MBTL1HTTKDM4E
SCHEMBL11211190 0.79 F12 (0.55) ALDH1A1CYP1A2HSD17B10L3MBTL1HTT
SCHEMBL11088904 0.78 ALDH1A1 (0.51) ALDH1A1CYP1A2HPGDHSD17B10DRD2
SCHEMBL14093917 0.78 ALDH1A1 (0.46) ALDH1A1CYP1A2HPGDHSD17B10DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893731-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK CO (US) 2004-01-28 EP disclosed
US-6306570-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY 2001-10-23 US disclosed
US-6054260-A Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 2000-04-25 US disclosed
EP-0893731-A1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 1999-01-27 EP disclosed