Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5580203 | 1.00 | KMT2A (0.55) | KMT2AALOX15HSD17B10CYP3A4KDM4E | |
| SCHEMBL15085673 | 1.00 | KMT2A (0.55) | KMT2AALOX15HSD17B10CYP3A4KDM4E | |
| SCHEMBL7276720 | 0.85 | KMT2A (0.46) | KMT2AALOX15HSD17B10CYP3A4KDM4E | |
| SCHEMBL25578544 | 0.85 | HDAC8 (0.48) | KMT2AALOX15HSD17B10CYP3A4KDM4E | |
| SCHEMBL29350881 | 0.85 | HDAC8 (0.58) | KMT2AALOX15HSD17B10CYP3A4KDM4E | |
| SCHEMBL44905 | 0.85 | HDAC8 (0.58) | KMT2AALOX15HSD17B10CYP3A4KDM4E | |
| SCHEMBL44904 | 0.85 | HDAC8 (0.58) | KMT2AALOX15HSD17B10CYP3A4KDM4E | |
| SCHEMBL1613174 | 0.85 | HDAC8 (0.58) | KMT2AALOX15HSD17B10CYP3A4KDM4E | |
| SCHEMBL28075883 | 0.84 | CYP3A4 (0.47) | KMT2AALOX15HSD17B10CYP3A4KDM4E | |
| SCHEMBL4140820 | 0.83 | KDM4E (0.66) | KMT2AALOX15HSD17B10CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382646-A1 | ENGINEERED ENZYMES AND METHODS FOR THE SYNTHESIS OF DIVERSE TYROSINE ANALOGS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2025-12-18 | — | — | US | claimed |
| US-12421534-B2 | Engineered enzymes and method for the synthesis of diverse tyrosine analogs | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2025-09-23 | — | — | US | claimed |
| US-20230313245-A1 | Engineered Enzymes and Method for the Synthesis of Diverse Tyrosine Analogs | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-10-05 | — | — | US | claimed |
| WO-2023086520-A2 | ENGINEERED ENZYMES AND METHOD FOR THE SYNTHESIS OF DIVERSE TYROSINE ANALOGS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-05-19 | — | — | WO | claimed |
| US-20250382646-A1 | ENGINEERED ENZYMES AND METHODS FOR THE SYNTHESIS OF DIVERSE TYROSINE ANALOGS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2025-12-18 | — | — | US | disclosed |
| US-12421534-B2 | Engineered enzymes and method for the synthesis of diverse tyrosine analogs | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2025-09-23 | — | — | US | disclosed |
| US-20230313245-A1 | Engineered Enzymes and Method for the Synthesis of Diverse Tyrosine Analogs | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-10-05 | — | — | US | disclosed |
| WO-2023086520-A2 | ENGINEERED ENZYMES AND METHOD FOR THE SYNTHESIS OF DIVERSE TYROSINE ANALOGS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-05-19 | — | — | WO | disclosed |
| EP-3655036-A1 | COMPOSITIONS FOR TREATING STRESS-RELATED DISORDERS | Hoffman Technologies, Inc. (US) | 2020-05-27 | — | — | EP | disclosed |
| CN-110769855-A | Compositions and methods for treating retinopathy | 史蒂文·霍夫曼 | 2020-02-07 | — | — | CN | disclosed |
| WO-2019018633-A1 | COMPOSITIONS FOR TREATING STRESS-RELATED DISORDERS | HOFFMAN TECHNOLOGIES, INC. (US) | 2019-01-24 | — | — | WO | disclosed |
| US-20070258899-A1 | Diagnostic and therapeutic agents | KARYON-CTT LTD (FI) | 2007-11-08 | — | — | US | disclosed |
| WO-2006017619-A2 | RECEPTOR-BINDING CYCLIC PEPTIDES AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-02-16 | — | — | WO | disclosed |
| US-20060029544-A1 | Receptor-binding cyclic peptides and methods of use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA OFFICE OF TECHNOLOGY TRANSFER (US) | 2006-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060029544-A1 | Receptor-binding cyclic peptides and methods of use | ITGB3, ITGB5, ITGA5 | KMT2A 4001/4885ALOX15 3927/4885HSD17B10 4773/4885 |
| US-20070258899-A1 | Diagnostic and therapeutic agents | YBX1, MLX, TPX2 | KMT2A 3586/4885ALOX15 4182/4885HSD17B10 4778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.