Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 14/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.39 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512676 | 0.90 | KIF11 (0.53) | KIF11 | |
| SCHEMBL5580632 | 0.79 | KIF11 (0.36) | KIF11EPHX2PLOD2PLOD3ALDH1A1 | |
| SCHEMBL5580307 | 0.77 | KIF11 (0.38) | KIF11MEN1KMT2AEPHX2PLOD2 | |
| SCHEMBL370451 | 0.74 | MIF (0.53) | KIF11MEN1KMT2AEPHX2PLOD2 | |
| SCHEMBL6244820 | 0.72 | KIF11 (0.46) | KIF11MEN1KMT2AEPHX2PLOD2 | |
| SCHEMBL34261 | 0.70 | KIF11 (0.56) | KIF11 | |
| SCHEMBL20701939 | 0.69 | KIF11 (0.40) | KIF11CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29053899 | 0.68 | KIF11 (0.68) | KIF11 | |
| SCHEMBL29053902 | 0.68 | KIF11 (0.68) | KIF11 | |
| SCHEMBL5580188 | 0.68 | KIF11 (0.36) | KIF11MEN1KMT2AEPHX2PLOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070264667-A1 | Method and system for assaying transferase activity | GELLIBOLIAN ROBERT | 2007-11-15 | — | — | US | disclosed |
| WO-2005024380-A9 | METHOD AND SYSTEM FOR ASSAYING TRANSFERASE ACTIVITY | GELLIBOLIAN ROBERT (US) | 2005-07-07 | — | — | WO | disclosed |
| WO-2005024380-A2 | METHOD AND SYSTEM FOR ASSAYING TRANSFERASE ACTIVITY | GELLIBOLIAN ROBERT (US) | 2005-03-17 | — | — | WO | disclosed |