Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10997776 | 0.83 | TBXAS1 (0.49) | TBXAS1NPC1RAB9AKMT2ATSHR | |
| SCHEMBL9294432 | 0.80 | TBXAS1 (0.58) | TBXAS1NPC1RAB9AKMT2ATSHR | |
| SCHEMBL28687106 | 0.79 | TBXAS1 (0.61) | TBXAS1NPC1RAB9AKMT2ATSHR | |
| SCHEMBL743343 | 0.78 | NPC1 (0.43) | TBXAS1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8736180 | 0.76 | TBXAS1 (0.47) | TBXAS1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL29163121 | 0.75 | NPC1 (0.47) | TBXAS1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL1237700 | 0.74 | NPC1 (0.43) | TBXAS1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL203700 | 0.74 | TBXAS1 (0.59) | TBXAS1KDM4E | |
| SCHEMBL9066509 | 0.74 | TBXAS1 (0.41) | TBXAS1NPC1RAB9AKMT2A | |
| SCHEMBL7052930 | 0.74 | ALDH1A1 (0.36) | TBXAS1NPC1RAB9AKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114375333-A | Compositions comprising a propeptide of lysyl oxidase and uses thereof | 耶达研究及发展有限公司 | 2022-04-19 | — | — | CN | disclosed |
| US-20070071752-A1 | Sphingosine kinase enzyme | JOHNSON & JOHNSON PHARMACEUTICAL R AND D LLC (US) | 2007-03-29 | — | — | US | disclosed |
| US-7112427-B2 | Sphingosine kinase enzyme | JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT LLC (US) | 2006-09-26 | — | — | US | disclosed |