Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 3/20 | 0.52 |
| ▸ | GHSR | Q92847 | 4/20 | 0.51 |
| ▸ | F2 | P00734 | 4/20 | 0.50 |
| ▸ | CALCR | P30988 | 4/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.49 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29351263 | 0.92 | CXCR4 (0.52) | APLNRTLR2 | |
| SCHEMBL10277277 | 0.91 | APLNR (0.52) | APLNRGHSRF2CALCRC5AR1 | |
| SCHEMBL15928124 | 0.86 | CXCR4 (0.50) | APLNRTLR2 | |
| SCHEMBL29473717 | 0.85 | CALCR (0.57) | APLNRF2CALCRC5AR1 | |
| SCHEMBL29473692 | 0.80 | OPRM1 (0.54) | APLNRF2C5AR1 | |
| SCHEMBL30617831 | 0.79 | F2 (0.58) | APLNRF2CALCRC5AR1 | |
| SCHEMBL30974276 | 0.78 | F2 (0.61) | APLNRF2CALCRC5AR1 | |
| SCHEMBL16684358 | 0.78 | F2 (0.65) | APLNRF2CALCR | |
| SCHEMBL15935518 | 0.78 | CXCR4 (0.53) | — | |
| SCHEMBL29842938 | 0.76 | CALCR (0.58) | APLNRF2CALCRC5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070071717-A1 | Treatment of B cells with IL-21 and B cell activators induces Granzyme B production | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2007-03-29 | — | — | US | disclosed |