Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 2/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PTGIR | P43119 | 1/20 | 0.43 |
| ▸ | CTSA | P10619 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5580545 | 1.00 | PSEN1 (0.48) | PSEN1PTGESALOX5PPARGPTGDR2 | |
| SCHEMBL5580791 | 0.88 | PSEN1 (0.47) | PSEN1PTGESALOX5PPARGPSEN2 | |
| SCHEMBL5580731 | 0.88 | PSEN1 (0.47) | PSEN1PTGESALOX5PPARGPSEN2 | |
| SCHEMBL5580784 | 0.88 | PSEN1 (0.47) | PSEN1PTGESALOX5PPARGPSEN2 | |
| SCHEMBL5580734 | 0.88 | PSEN1 (0.47) | PSEN1PTGESALOX5PPARGPSEN2 | |
| SCHEMBL5580737 | 0.88 | PPARD (0.41) | PSEN1PTGESALOX5PPARGPTGDR2 | |
| SCHEMBL5580733 | 0.88 | PPARD (0.41) | PSEN1PTGESALOX5PPARGPTGDR2 | |
| SCHEMBL3508227 | 0.86 | PPARG (0.49) | PSEN1PTGESALOX5PPARGPTGDR2 | |
| SCHEMBL3508229 | 0.86 | PPARG (0.49) | PSEN1PTGESALOX5PPARGPTGDR2 | |
| SCHEMBL5580428 | 0.86 | RXRA (0.46) | PSEN1PTGESALOX5PPARGPSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105959-A1 | Cynnamyl alcohol derivative compounds and drugs containing the compounds as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-10 | — | — | US | claimed |
| EP-1604971-A1 | CINNAMYL ALCOHOL DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-12-14 | — | — | EP | claimed |
| US-20070105959-A1 | Cynnamyl alcohol derivative compounds and drugs containing the compounds as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
| EP-1604971-A1 | CINNAMYL ALCOHOL DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-12-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105959-A1 | Cynnamyl alcohol derivative compounds and drugs containing the compounds as active ingredient | LPL, GPR119, EBP | PSEN1 3648/4885PTGES 783/4885ALOX5 1218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.