Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 9/20 | 0.42 |
| ▸ | PLG | P00747 | 7/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | GRK5 | P34947 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5580944 | 0.92 | PLAU (0.48) | PLAUPLGCLK4PLATIKBKB | |
| SCHEMBL5581446 | 0.78 | PLAU (0.47) | PLAUPLGPLAT | |
| SCHEMBL5580874 | 0.78 | PLAU (0.51) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL5580908 | 0.76 | PLAU (0.56) | PLAUPLGPLATCFDLOXL2 | |
| SCHEMBL5581641 | 0.76 | PLAU (0.52) | PLAUPLGPLAT | |
| SCHEMBL5581586 | 0.75 | PLAU (0.47) | PLAUPLGPLATCFD | |
| SCHEMBL5475393 | 0.74 | LOXL2 (0.57) | PLAUPLGCSF1RKDRGSK3A | |
| SCHEMBL5581364 | 0.74 | PLAU (0.50) | PLAUPLGPLATCFD | |
| Hydrochloric Acid SCHEMBL5581873 | 0.73 | PLAU (0.47) | PLAUPLGPLATLOXL2 | |
| Hydrochloric Acid SCHEMBL5581213 | 0.72 | PLAU (0.46) | PLAUPLGPLATCFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148164-A1 | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto | BIOGEN IDEC MA INC. (US) | 2007-06-28 | — | — | US | disclosed |