Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 10/20 | 0.46 |
| ▸ | PLG | P00747 | 7/20 | 0.46 |
| ▸ | PLAT | P00750 | 4/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5581264 | 0.84 | PLAU (0.51) | PLAUPLGPLATPTGER2CFD | |
| SCHEMBL5580866 | 0.74 | PLAU (0.50) | PLAUPLGPLATCFD | |
| SCHEMBL5581919 | 0.73 | PLAU (0.47) | PLAUPLGPLATCFD | |
| SCHEMBL5580672 | 0.70 | PLAU (0.51) | PLAUPLGPLAT | |
| SCHEMBL5581171 | 0.70 | PLAU (0.57) | PLAUPLGPLATCFD | |
| SCHEMBL5580722 | 0.68 | PLAU (0.62) | PLAUPLGPLATCFD | |
| SCHEMBL5580775 | 0.68 | PLAU (0.53) | PLAUPLGPLATPTGER2CFD | |
| SCHEMBL5581364 | 0.68 | PLAU (0.50) | PLAUPLGPLATCFD | |
| SCHEMBL2476019 | 0.68 | ADRA2C (0.51) | PDCD1CD274ADRA2C | |
| SCHEMBL5581451 | 0.67 | PLAU (0.54) | PLAUPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148164-A1 | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto | BIOGEN IDEC MA INC. (US) | 2007-06-28 | — | — | US | disclosed |