SCHEMBL5581831

SCHEMBL5581831

O=C(NCCOP(=O)(O)O)OCc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.70
▸ SMN1; SMN2 Q16637 1/20 0.70
▸ HTT P42858 1/20 0.58
▸ L3MBTL1 Q9Y468 2/20 0.58
▸ MAPT P10636 1/20 0.56
▸ TGM2 P21980 1/20 0.52
▸ KEAP1 Q14145 2/20 0.51
▸ NFE2L2 Q16236 2/20 0.51
▸ SLC1A3 P43003 1/20 0.49
▸ SLC1A1 P43005 1/20 0.49
▸ MEN1 O00255 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ TSHR P16473 1/20 0.47
▸ HSD17B10 Q99714 1/20 0.47
▸ KAT2B Q92831 1/20 0.46
▸ GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24486768 0.92 HTT (0.63) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL29592964 0.87 LMNA (0.68) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL8189834 0.86 LMNA (0.63) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL9932079 0.85 LMNA (0.62) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL4312519 0.85 LMNA (0.56) LMNASMN1; SMN2HTTL3MBTL1TGM2
SCHEMBL21171855 0.84 SMN1; SMN2 (0.49) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL21533723 0.84 LMNA (0.50) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL9932446 0.83 LMNA (0.63) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL5063193 0.83 LMNA (0.77) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL7372302 0.83 SMN1; SMN2 (1.00) LMNASMN1; SMN2HTTL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114591361-B Preparation method of (R) -glycerophosphatidylethanolamine 苏州昊帆生物股份有限公司 2024-04-26 — — CN claimed
CN-114591361-B Preparation method of (R) -glycerophosphatidylethanolamine 苏州昊帆生物股份有限公司 2024-04-26 — — CN disclosed
CN-114591361-B Preparation method of (R) -glycerophosphatidylethanolamine 苏州昊帆生物股份有限公司 2024-04-26 — — CN disclosed
US-20220412963-A1 FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES THROUGH REDUCTIVE AMINATION FOR ENHANCED MS SIGNALS WATERS TECHNOLOGIES CORPORATION 2022-12-29 — — US disclosed
US-11353461-B2 Methods of enhancing MS detection of tagged glycans WATERS TECHNOLOGIES CORPORATION (US) 2022-06-07 — — US disclosed
US-11061023-B2 Fluorescence tagging of glycans and other biomolecules through reductive amination for enhanced MS signals WATERS TECHNOLOGIES CORPORATION (US) 2021-07-13 — — US disclosed
US-20190331669-A1 FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES THROUGH REDUCTIVE AMINATION FOR ENHANCED MS SIGNALS WATERS TECHNOLOGIES CORPORATION (US) 2019-10-31 — — US disclosed
US-20190219587-A1 METHODS OF ENHANCING MS DETECTION OF TAGGED GLYCANS WATERS TECHNOLOGIES CORPORATION 2019-07-18 — — US disclosed
US-20070264667-A1 Method and system for assaying transferase activity GELLIBOLIAN ROBERT 2007-11-15 — — US disclosed
WO-2005024380-A9 METHOD AND SYSTEM FOR ASSAYING TRANSFERASE ACTIVITY GELLIBOLIAN ROBERT (US) 2005-07-07 — — WO disclosed
WO-2005024380-A2 METHOD AND SYSTEM FOR ASSAYING TRANSFERASE ACTIVITY GELLIBOLIAN ROBERT (US) 2005-03-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190331669-A1 FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES THROUGH REDUCTIVE AMINATION FOR ENHANCED MS SIGNALS FUT5, FUT6, OGT LMNA 1541/4885SMN1; SMN2 4264/4885HTT 1546/4885
US-20220412963-A1 FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES THROUGH REDUCTIVE AMINATION FOR ENHANCED MS SIGNALS FUT5, FUT6, OGT LMNA 1541/4885SMN1; SMN2 4264/4885HTT 1546/4885
US-11061023-B2 Fluorescence tagging of glycans and other biomolecules through reductive amination for enhanced MS signals FUT5, FUT6, OGT LMNA 1541/4885SMN1; SMN2 4264/4885HTT 1546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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