Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 13/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5582061 | 0.84 | NQO2 (0.43) | NQO2ALDH1A1 | |
| SCHEMBL5582304 | 0.78 | NQO2 (0.45) | NQO2 | |
| SCHEMBL5582326 | 0.75 | CRHR1 (0.35) | CRHR1TAAR1ALDH1A1 | |
| SCHEMBL30527150 | 0.75 | NQO2 (0.45) | NQO2ALDH1A1 | |
| SCHEMBL25903679 | 0.75 | NQO2 (0.45) | NQO2ALDH1A1 | |
| SCHEMBL5582308 | 0.74 | MEN1 (0.38) | CRHR1TAAR1ALDH1A1 | |
| SCHEMBL5581805 | 0.72 | NQO2 (0.43) | NQO2 | |
| SCHEMBL2170435 | 0.69 | NQO2 (0.45) | NQO2TDP1ALDH1A1 | |
| SCHEMBL2170898 | 0.69 | PDE4B (0.50) | CRHR1NQO2ALDH1A1 | |
| SCHEMBL4700757 | 0.67 | PDE4A (0.50) | NQO2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225308-A1 | 2-Amino Quinazoline Derivative | KYOWA HAKKO KOGYO CO.,LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
| EP-1726584-A1 | 2-AMINOQUINAZOLINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225308-A1 | 2-Amino Quinazoline Derivative | AGTR2, ABL1, AGTR1 | CRHR1 457/4885NQO2 7/4885TAAR1 360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.