Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5582085 | 0.84 | CSNK2A2 (0.38) | CSNK2A2CSNK2BCSNK2A1ADORA1DHFR | |
| SCHEMBL5582020 | 0.83 | ADORA1 (0.40) | CSNK2A2CSNK2BCSNK2A1ADORA1DHFR | |
| SCHEMBL5581986 | 0.81 | CSNK2A2 (0.36) | CSNK2A2CSNK2BCSNK2A1ADORA1DHFR | |
| SCHEMBL5582309 | 0.80 | CSNK2A1 (0.52) | CSNK2A2CSNK2BCSNK2A1ADORA1MAP4K4 | |
| SCHEMBL5581799 | 0.80 | FYN (0.41) | CSNK2A2CSNK2BCSNK2A1ADORA1DHFR | |
| SCHEMBL5582071 | 0.78 | FYN (0.39) | CSNK2A2CSNK2BCSNK2A1ADORA1MAP4K4 | |
| SCHEMBL5582299 | 0.77 | CSNK2A2 (0.37) | CSNK2A2CSNK2BCSNK2A1ADORA1MAP4K4 | |
| SCHEMBL5581770 | 0.77 | ADORA1 (0.40) | CSNK2A2CSNK2BCSNK2A1ADORA1MAP4K4 | |
| SCHEMBL5582247 | 0.76 | ADORA1 (0.39) | CSNK2A2CSNK2BCSNK2A1ADORA1NUDT1 | |
| SCHEMBL5582307 | 0.76 | PDE4B (0.41) | CSNK2A2CSNK2BCSNK2A1ADORA1NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225308-A1 | 2-Amino Quinazoline Derivative | KYOWA HAKKO KOGYO CO.,LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
| EP-1726584-A1 | 2-AMINOQUINAZOLINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225308-A1 | 2-Amino Quinazoline Derivative | AGTR2, ABL1, AGTR1 | CSNK2A2 467/4885CSNK2B 662/4885CSNK2A1 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.