SCHEMBL5582154

SCHEMBL5582154

[c]1cc(C2CCCCC2)c[c]c1C1CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 1/20 0.36
KMO O15229 1/20 0.32
HTT P42858 2/20 0.32
KMT2A Q03164 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
KDM4E B2RXH2 1/20 0.32
GLA P06280 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
LMNA P02545 1/20 0.32
ACMSD Q8TDX5 1/20 0.32
TDO2 P48775 1/20 0.31
HSP90AA1 P07900 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
BACE1 P56817 1/20 0.31
NOTUM Q6P988 1/20 0.31
SLC18A3 Q16572 1/20 0.31
HDAC1 Q13547 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5349384 0.73 CYP11B2 (0.38) CYP11B2KMOHTTKMT2ATDP1
SCHEMBL1779002 0.71 CYP11B2 (0.37) CYP11B2KMOHTTKMT2ATDP1
SCHEMBL2254634 0.70 CYP11B2 (0.39) CYP11B2KMOHTTKMT2ATDP1
SCHEMBL778084 0.70 CYP11B2 (0.46) CYP11B2KMOHTTKMT2ATDP1
SCHEMBL192810 0.70 LMNA (0.37) CYP11B2HTTKMT2ATDP1KDM4E
SCHEMBL28878467 0.70 CYP11B2 (0.36) CYP11B2HTTKMT2ATDP1KDM4E
SCHEMBL28342563 0.68 HDAC8 (0.36) CYP11B2HTTKMT2ATDP1KDM4E
SCHEMBL6275125 0.68 HDAC8 (0.52) CYP11B2HTTKMT2ATDP1KDM4E
SCHEMBL15260520 0.68 HDAC8 (0.52) CYP11B2HTTKMT2ATDP1KDM4E
SCHEMBL28584923 0.68 HDAC8 (0.52) CYP11B2HTTKMT2ATDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148480-A1 Laminate TEIJIN LIMITED (JP) 2007-06-28 US disclosed
EP-1698460-A1 MULTILAYER BODY TEIJIN LIMITED (JP) 2006-09-06 EP disclosed
US-20060134407-A1 Adhesive sheet and layered product TEIJIN LIMITED (JP) 2006-06-22 US disclosed
EP-1589086-A1 ADHESIVE SHEET AND LAYERED PRODUCT TEIJIN LIMITED (JP) 2005-10-26 EP disclosed