Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38584 | 0.79 | TDP1 (0.41) | ALDH1A1TDP1HSD17B10CYP2A6TSHR | |
| SCHEMBL29500990 | 0.79 | TDP1 (0.41) | ALDH1A1TDP1HSD17B10CYP2A6TSHR | |
| SCHEMBL28080025 | 0.79 | SENP2 (0.44) | ALDH1A1TDP1HSD17B10CYP2A6TSHR | |
| SCHEMBL7195938 | 0.78 | THRB (0.54) | ALDH1A1TDP1HSD17B10PAX8HPGD | |
| SCHEMBL31148851 | 0.78 | TSHR (0.48) | ALDH1A1TDP1HSD17B10CYP2A6TSHR | |
| SCHEMBL1900115 | 0.78 | CYP2A6 (0.48) | ALDH1A1TDP1HSD17B10CYP2A6TSHR | |
| SCHEMBL17472993 | 0.78 | TSHR (0.48) | ALDH1A1TDP1HSD17B10CYP2A6TSHR | |
| SCHEMBL1897887 | 0.78 | ALDH1A1 (0.39) | ALDH1A1TDP1HSD17B10CYP2A6TSHR | |
| SCHEMBL3713908 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TDP1HSD17B10CYP2A6TSHR | |
| SCHEMBL7191223 | 0.75 | POLB (0.40) | ALDH1A1TDP1HSD17B10CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037808-A1 | p38 kinase inhibitors | DECIPHERA PHARMACEUTICALS, LLC | 2007-02-15 | — | — | US | disclosed |
| US-5571779-A | SKI WAXES | RFC TECHNOLOGY, INC. | 1996-11-05 | — | — | US | disclosed |
| US-5502225-A | SKI WAXES | DYNAX CORPORATION (US) | 1996-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037808-A1 | p38 kinase inhibitors | MAPK1, MAP3K8, MAP3K1 | ALDH1A1 3608/4885TDP1 1232/4885HSD17B10 4164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.