Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 5/20 | 0.41 |
| ▸ | BCR | P11274 | 5/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.39 |
| ▸ | CYP2A7 | P20853 | 2/20 | 0.39 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.39 |
| ▸ | CYP2F1 | P24903 | 2/20 | 0.39 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257740 | 0.84 | ALDH1A1 (0.40) | ALDH1A1CYP1A1CYP1B1CYP3A4ABL1 | |
| SCHEMBL7007855 | 0.77 | ACHE (0.50) | ALDH1A1CYP3A4CA1CA2NPC1 | |
| 1,3,5-Trimethoxybenzene SCHEMBL28493 | 0.76 | ALDH1A1 (1.00) | ALDH1A1CYP1A1CYP1B1CYP3A4ABL1 | |
| SCHEMBL14500179 | 0.76 | ALDH1A1 (0.61) | ALDH1A1CYP1A1CYP1B1CYP3A4ABL1 | |
| SCHEMBL13798720 | 0.75 | CYP1A1 (0.41) | ALDH1A1CYP1A1CYP1B1CYP3A4CYP1A2 | |
| SCHEMBL16303509 | 0.74 | ALDH1A1 (0.58) | ALDH1A1CYP1A1CYP1B1CYP3A4ABL1 | |
| SCHEMBL3261919 | 0.74 | CA1 (0.58) | ALDH1A1CYP3A4CA1CA2KDM4E | |
| SCHEMBL1402759 | 0.74 | ALDH1A1 (0.79) | ALDH1A1CYP1A1CYP1B1CYP3A4ABL1 | |
| 1,3,5-Trimethoxybenzene SCHEMBL28740008 | 0.73 | ALDH1A1 (0.92) | ALDH1A1CYP1A1CYP1B1CYP3A4ABL1 | |
| 1,3,5-Trimethoxybenzene SCHEMBL28416912 | 0.73 | ALDH1A1 (0.92) | ALDH1A1CYP1A1CYP1B1CYP3A4ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184521-A1 | INDAZOLE COMPOUNDS AS FGFR KINASE INHIBITOR, PREPARATION AND USE THEREOF | Shanghai Haihe Pharmaceutical Co., Ltd. (CN) | 2017-06-28 | — | — | EP | disclosed |
| US-8269317-B2 | Phosphorescent materials | UNIVERSAL DISPLAY CORPORATION (US) | 2012-09-18 | — | — | US | disclosed |
| WO-2012064499-A1 | PHOSPHORESCENT MATERIALS | UNIVERSAL DISPLAY CORPORATION (US) | 2012-05-18 | — | — | WO | disclosed |
| US-20120119190-A1 | PHOSPHORESCENT MATERIALS | UNIVERSAL DISPLAY CORPORATION (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120119190-A1 | PHOSPHORESCENT MATERIALS | RECQL, POLQ, IK | ALDH1A1 3188/4885CYP1A1 2244/4885CYP1B1 2892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.