Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28482210 | 0.82 | ACHE (0.54) | ACHECES2CES1ENPP2CA1 | |
| 1,3-Dimethoxybenzene SCHEMBL2348353 | 0.81 | ACHE (0.58) | ACHECES2CES1ENPP2CA1 | |
| SCHEMBL12464036 | 0.80 | ACHE (0.52) | ACHECES2CES1ENPP2CA1 | |
| SCHEMBL28277390 | 0.78 | ACHE (0.50) | ACHECES2CES1ENPP2CA1 | |
| SCHEMBL23018998 | 0.78 | TP53 (0.53) | ALDH1A1CYP3A4LMNA | |
| SCHEMBL17643580 | 0.77 | MAPK1 (0.43) | ALDH1A1LMNA | |
| SCHEMBL23192517 | 0.77 | CYP1A2 (0.54) | ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL5582461 | 0.77 | ALDH1A1 (0.58) | CA1CA2ALDH1A1CYP3A4NPC1 | |
| 1,3-Dimethoxybenzene SCHEMBL27700724 | 0.76 | ACHE (0.64) | ACHECES2CES1ENPP2CA1 | |
| 1,3-Dimethoxybenzene SCHEMBL9350 | 0.75 | ACHE (0.70) | ACHECES2CES1ENPP2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081928-A1 | TRICYCLIC HETEROBIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF TARGETED PROTEINS | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2020160180-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |
| EP-3524602-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Haihe Pharmaceutical Co., Ltd. (CN) | 2019-08-14 | — | — | EP | disclosed |
| EP-3013823-B1 | IMIDAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-11-01 | — | — | EP | disclosed |
| WO-2017023988-A1 | 3-(3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-1H-PYRAZOLO[4,3-B]PYRIDINES AND THERAPEUTIC USES THEREOF | SAMUMED, LLC. (US) | 2017-02-09 | — | — | WO | disclosed |
| US-8269317-B2 | Phosphorescent materials | UNIVERSAL DISPLAY CORPORATION (US) | 2012-09-18 | — | — | US | disclosed |
| WO-2012064499-A1 | PHOSPHORESCENT MATERIALS | UNIVERSAL DISPLAY CORPORATION (US) | 2012-05-18 | — | — | WO | disclosed |
| US-20120119190-A1 | PHOSPHORESCENT MATERIALS | UNIVERSAL DISPLAY CORPORATION (US) | 2012-05-17 | — | — | US | disclosed |
| EP-1619177-B1 | ORGANIC ELECTROLUMINESCENCE ELEMENT | FUJIFILM CORP (JP) | 2008-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120119190-A1 | PHOSPHORESCENT MATERIALS | RECQL, POLQ, IK | ACHE 284/4885CES2 4582/4885CES1 4857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.