SCHEMBL558262

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL558261	0.88	AKT1 (0.35)	AKT1AKT2
	SCHEMBL6544085	0.78	—	—
	SCHEMBL3575254	0.77	ADORA1 (0.39)	AKT1AKT2
	SCHEMBL5612902	0.72	AKT1 (0.41)	AKT1AKT2
	SCHEMBL31231553	0.72	AKT1 (0.41)	AKT1AKT2
	SCHEMBL9868	0.71	AKT1 (0.46)	AKT1AKT2
	SCHEMBL17443257	0.71	PTGS2 (0.43)	AKT1AKT2
	SCHEMBL6741233	0.69	AKT1 (0.45)	AKT1AKT2
	SCHEMBL28531472	0.69	AKT1 (0.45)	AKT1AKT2
	SCHEMBL18952645	0.69	ADORA1 (0.39)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.