Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 5/20 | 0.77 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.77 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.77 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.70 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.67 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.66 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.64 |
| ▸ | PTGES | O14684 | 2/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.64 |
| ▸ | RXRA | P19793 | 1/20 | 0.63 |
| ▸ | RXRB | P28702 | 1/20 | 0.63 |
| ▸ | RXRG | P48443 | 1/20 | 0.63 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.62 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.62 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.62 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949143 | 0.92 | NR4A2 (0.90) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL7477872 | 0.91 | MRGPRX4 (0.74) | NR4A2NR4A1NR4A3SRD5A2MRGPRX4 | |
| SCHEMBL10459767 | 0.91 | MRGPRX4 (0.79) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL1756343 | 0.91 | NR4A2 (0.81) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL5582767 | 0.91 | NR4A2 (0.81) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| Hydrochloric Acid SCHEMBL8378883 | 0.91 | NR4A2 (0.87) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL17952637 | 0.88 | NR4A2 (0.71) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL4059143 | 0.87 | NR4A2 (1.00) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL228477 | 0.87 | NR4A2 (1.00) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL6830467 | 0.87 | NR4A2 (1.00) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2990459-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2017-04-26 | — | — | EP | disclosed |
| US-9594283-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-03-14 | — | — | US | disclosed |