SCHEMBL5582805

SCHEMBL5582805

CCN(CC)CCc1cc(NC(=O)c2ccc(-c3ccccc3)cc2)ccc1C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MCHR1 Q99705 10/20 0.64
▸ TDP1 Q9NUW8 2/20 0.50
▸ GALK1 P51570 1/20 0.48
▸ CASP6 P55212 1/20 0.48
▸ MCL1 Q07820 1/20 0.48
▸ PLEC Q15149 1/20 0.48
▸ KMT2A Q03164 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ LMNA P02545 1/20 0.47
▸ MAPT P10636 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ PKM P14618 1/20 0.47
▸ DEGS1 O15121 1/20 0.46
▸ PTPN1 P18031 1/20 0.46
▸ TRPV1 Q8NER1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3073675 0.82 MAPT (0.56) TDP1KMT2AMEN1LMNAMAPT
SCHEMBL5925633 0.78 TERT (0.37) MCHR1SMN1; SMN2
SCHEMBL20335185 0.77 ALDH1A1 (0.37) MCHR1KMT2AKDM4EMEN1SMN1; SMN2
SCHEMBL5583042 0.76 TDP1 (0.81) MCHR1TDP1KMT2AKDM4EMEN1
SCHEMBL5582801 0.76 MCHR1 (0.55) MCHR1TDP1GALK1CASP6MCL1
SCHEMBL3296397 0.74 KMT2A (0.83) TDP1GALK1CASP6MCL1PLEC
SCHEMBL13656220 0.74 MCHR1 (0.49) MCHR1KMT2AKDM4EMEN1MAPT
SCHEMBL5582633 0.74 SMN1; SMN2 (0.69) MCHR1TDP1KMT2AKDM4EMEN1
SCHEMBL13660199 0.73 MCHR1 (0.79) MCHR1KMT2AKDM4EMEN1LMNA
SCHEMBL6925692 0.73 MCHR1 (0.92) MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070173498-A1 Melanin concentrating hormone antagonist KATO KANEYOSHI 2007-07-26 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070173498-A1 Melanin concentrating hormone antagonist MC1R, MCHR1, MCHR2 MCHR1 2/4885TDP1 4545/4885GALK1 4443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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