Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.55 |
| ▸ | GALK1 | P51570 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | PLEC | Q15149 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20335182 | 0.77 | ALDH1A1 (0.37) | TDP1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL5582805 | 0.76 | MCHR1 (0.64) | MCHR1GALK1CASP6MCL1PLEC | |
| SCHEMBL3296397 | 0.74 | KMT2A (0.83) | GALK1CASP6MCL1PLECTDP1 | |
| SCHEMBL6925688 | 0.73 | MCHR1 (0.63) | MCHR1SMN1; SMN2HTR2CTRPV1 | |
| SCHEMBL3296193 | 0.72 | MCHR1 (0.69) | MCHR1GALK1CASP6MCL1PLEC | |
| SCHEMBL2398892 | 0.72 | PGR (0.49) | TDP1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL10758235 | 0.72 | SIRT6 (0.64) | GALK1CASP6MCL1PLECTDP1 | |
| SCHEMBL19285837 | 0.71 | NR1I3 (0.34) | KMT2AKDM4ELMNAMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11581399 | 0.71 | PGR (0.47) | TDP1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL18030845 | 0.70 | NR1H4 (0.67) | MCHR1KMT2AKDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070173498-A1 | Melanin concentrating hormone antagonist | KATO KANEYOSHI | 2007-07-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173498-A1 | Melanin concentrating hormone antagonist | MC1R, MCHR1, MCHR2 | MCHR1 2/4885GALK1 4443/4885CASP6 4819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.