Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.58 |
| ▸ | SCN1A | P35498 | 1/20 | 0.58 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.58 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.58 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.55 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6075399 | 0.85 | CHRNB4 (0.50) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL1011265 | 0.80 | CHRNB4 (0.51) | ADRA2ACHRNB4CHRNA3ALDH1A1MEN1 | |
| SCHEMBL16715355 | 0.80 | CHRNB4 (0.54) | ADRA2AADRA2BADRA2CCHRNB4CHRNA3 | |
| SCHEMBL1011267 | 0.80 | CHRNB4 (0.51) | ADRA2ACHRNB4CHRNA3ALDH1A1MEN1 | |
| SCHEMBL6925938 | 0.80 | CHRNB4 (0.51) | CHRNB4CHRNA3ALDH1A1MEN1KMT2A | |
| SCHEMBL5846431 | 0.80 | CHRNB4 (0.51) | CHRNB4CHRNA3ALDH1A1MEN1KMT2A | |
| SCHEMBL5582527 | 0.78 | ALDH1A1 (0.48) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL5398026 | 0.78 | ADRA2A (0.65) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL5582594 | 0.77 | CHRNB4 (0.51) | ADRA2AADRA2BADRA2CCHRNB4CHRNA3 | |
| SCHEMBL5937030 | 0.77 | CHRNB4 (0.51) | ADRA2AADRA2BADRA2CCHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070173498-A1 | Melanin concentrating hormone antagonist | KATO KANEYOSHI | 2007-07-26 | — | — | US | disclosed |
| US-7115750-B1 | Melanin concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173498-A1 | Melanin concentrating hormone antagonist | MC1R, MCHR1, MCHR2 | ADRA2A 204/4885ADRA2B 197/4885ADRA2C 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.