SCHEMBL3732273

SCHEMBL3732273

CCCCCOP(=O)(Cl)ON1CCOCC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25A P30304 2/20 0.44
LPAR3 Q9UBY5 3/20 0.39
LPAR1 Q92633 2/20 0.39
LPAR2 Q9HBW0 2/20 0.39
LMNA P02545 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
POLB P06746 1/20 0.38
RAB9A P51151 2/20 0.35
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.35
TP53 P04637 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP3A4 P08684 1/20 0.35
THRB P10828 6/20 0.34
MAPK1 P28482 2/20 0.34
KCNH2 Q12809 2/20 0.34
ALDH1A1 P00352 1/20 0.34
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8467492 0.83 CYP3A4 (0.48) CDC25ALPAR3LPAR1LPAR2LMNA
SCHEMBL5582947 0.83 CDC25A (0.48) CDC25ALPAR3LPAR1LPAR2LMNA
SCHEMBL5672809 0.82 CDC25A (0.42) CDC25ALPAR3LPAR1LPAR2LMNA
SCHEMBL8721057 0.82 KMT2A (0.43) LMNASMN1; SMN2POLBRAB9AMEN1
SCHEMBL4365735 0.76 MMP1 (0.35) MEN1KMT2A
SCHEMBL8378718 0.74 CDC25A (0.41) CDC25ALPAR3LPAR1LPAR2LMNA
SCHEMBL178106 0.74 LPAR3 (0.58) CDC25ALPAR3LPAR1LPAR2LMNA
SCHEMBL9819673 0.73 TSHR (0.34) TSHRKMT2AALDH1A1USP2
SCHEMBL24172978 0.72 LPAR3 (0.61) CDC25ALPAR3LPAR1LPAR2LMNA
SCHEMBL177971 0.72 LPAR3 (0.61) CDC25ALPAR3LPAR1LPAR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6576161-B2 Polyphosphate ester morpholides, mixtures thereof, and thermoplastic resin compositions containing polyphosphate ester morpholides as flame retardants CHEIL INDUSTRIES, INC. (KR) 2003-06-10 US claimed
US-20020091180-A1 Polyphosphate ester morpholides, mixtures thereof, and thermoplastic resin compositions containing polyphosphate ester morpholides as flame retardants CHEIL INDUSTRIES INC. (KR) 2002-07-11 US claimed
US-7691924-B2 Flame retardant thermoplastic resin composition CHEIL INDUSTRIES (KR) 2010-04-06 US disclosed
US-7550523-B2 Thermoplastic resin compositions containing mixtures of cyclic phosphazenes and phosphate ester morpholides CHEIL INDUSTRIES INC. (KR) 2009-06-23 US disclosed
US-20080182926-A1 Flame retardant thermoplastic resin composition CHEIL INDUSTRIES (KR) 2008-07-31 US disclosed
EP-1425347-B1 FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITION CHEIL IND INC (KR) 2007-05-16 EP disclosed
EP-1209163-B1 Oligomeric phosphoric acid ester morpholide compound and flame retardant thermoplastic resin composition containing the same CHEIL IND INC (KR) 2006-01-25 EP disclosed
US-6900256-B2 Thermoplastic resin compositions containing polyphosphate ester morpholides as flame retardants CHEIL INDUSTRIES INC. (KR) 2005-05-31 US disclosed
EP-1425347-A4 FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITION CHEIL IND INC (KR) 2005-01-26 EP disclosed
US-20040249027-A1 Flame retardant thermoplastic resin composition CHEIL INDUSTRIES INC. (KR) 2004-12-09 US disclosed
EP-1425347-A1 FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITION Cheil Industries Inc. (KR) 2004-06-09 EP disclosed
EP-1207182-B1 Flame retardant thermoplastic resin composition CHEIL IND INC (KR) 2004-04-07 EP disclosed
US-6576161-B2 Polyphosphate ester morpholides, mixtures thereof, and thermoplastic resin compositions containing polyphosphate ester morpholides as flame retardants CHEIL INDUSTRIES, INC. (KR) 2003-06-10 US disclosed
WO-2003022928-A1 FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITION CHEIL INDUSTRIES INC. (KR) 2003-03-20 WO disclosed
US-20030040560-A1 Thermoplastic resin compositions containing polyphosphate ester morpholides as flame retardants CHEIL INDUSTRIES INC. (KR) 2003-02-27 US disclosed
US-20020091180-A1 Polyphosphate ester morpholides, mixtures thereof, and thermoplastic resin compositions containing polyphosphate ester morpholides as flame retardants CHEIL INDUSTRIES INC. (KR) 2002-07-11 US disclosed
EP-1209163-A1 Oligomeric phosphoric acid ester morpholide compound and flame retardant thermoplastic resin composition containing the same Cheil Industries Inc. (KR) 2002-05-29 EP disclosed
EP-1207182-A1 Flame retardant thermoplastic resin composition Cheil Industries Inc. (KR) 2002-05-22 EP disclosed