SCHEMBL8378588

SCHEMBL8378588

CCCCCCCC(F)CCOP(=O)(ON1CCOCC1)ON1CCOCC1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CDC25A P30304 1/20 0.36
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP3A4 P08684 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SMPD1 P17405 3/20 0.31
THRA P10827 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5057044 0.99 CDC25A (0.34) CDC25ALMNAPOLBSMN1; SMN2CYP3A4
SCHEMBL8378718 0.95 CDC25A (0.41) CDC25ALMNAPOLBSMN1; SMN2CYP3A4
SCHEMBL5582947 0.84 CDC25A (0.48) CDC25ALMNAPOLBSMN1; SMN2CYP3A4
SCHEMBL8467492 0.81 CYP3A4 (0.48) CDC25ALMNAPOLBSMN1; SMN2CYP3A4
SCHEMBL8617901 0.81 CDC25A (0.32) CDC25ALMNAPOLBSMN1; SMN2CYP3A4
SCHEMBL5672809 0.75 CDC25A (0.42) CDC25ALMNAPOLBSMN1; SMN2CYP3A4
SCHEMBL8378684 0.73 FDPS (0.30)
SCHEMBL4923399 0.70
SCHEMBL3732273 0.69 CDC25A (0.44) CDC25ALMNAPOLBSMN1; SMN2CYP3A4
SCHEMBL5054747 0.69 FDPS (0.46) SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788347-B1 STABLE REVERSE AND MULTIPLE FLUOROCARBON EMULSIONS ALLIANCE PHARMA (US) 1999-08-11 EP disclosed
US-5904933-A Stable reverse and multiple fluorocarbon emulsions ALLIANCE PHARMACEUTICAL CORP. (US) 1999-05-18 US disclosed
EP-0788347-A1 STABLE REVERSE AND MULTIPLE FLUOROCARBON EMULSIONS ALLIANCE PHARMACEUTICAL CORPORATION (US) 1997-08-13 EP disclosed
WO-1995033447-A1 STABLE REVERSE AND MULTIPLE FLUOROCARBON EMULSIONS ALLIANCE PHARMACEUTICAL CORP. (GB) 1995-12-14 WO disclosed