Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.49 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.49 |
| ▸ | ULK1 | O75385 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2323451 | 0.84 | HSD11B1 (0.49) | KMT2ACYP2D6KDM4EMAPTATM | |
| SCHEMBL7001156 | 0.84 | KMT2A (0.64) | KMT2ACYP2D6KDM4EMAPTATM | |
| SCHEMBL4671412 | 0.84 | MGLL (0.49) | KMT2ACYP2D6KDM4EMAPTATM | |
| SCHEMBL638646 | 0.83 | SLC6A1 (0.56) | KMT2ACYP2D6KDM4EMAPTATM | |
| Hydrochloric Acid SCHEMBL5478791 | 0.83 | HSD11B1 (0.48) | KMT2ACYP2D6KDM4EMAPTATM | |
| Hydrochloric Acid SCHEMBL4028302 | 0.82 | SLC6A1 (0.55) | KMT2ACYP2D6KDM4EMAPTATM | |
| SCHEMBL16615303 | 0.81 | SRD5A2 (0.59) | KMT2ACYP2D6MEN1MGLLSRD5A2 | |
| SCHEMBL11799390 | 0.80 | SLC6A1 (0.45) | KMT2ACYP2D6KDM4EMAPTATM | |
| SCHEMBL11798075 | 0.80 | NPC1 (0.59) | KMT2ASLC6A1SLC6A11LMNASMN1; SMN2 | |
| SCHEMBL18203121 | 0.80 | MEN1 (0.67) | KMT2ACYP2D6TSHRMEN1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070173498-A1 | Melanin concentrating hormone antagonist | KATO KANEYOSHI | 2007-07-26 | — | — | US | disclosed |
| US-7115750-B1 | Melanin concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173498-A1 | Melanin concentrating hormone antagonist | MC1R, MCHR1, MCHR2 | KMT2A 1886/4885CYP2D6 2688/4885KDM4E 2952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.