Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.56 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | F12 | P00748 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17122454 | 0.92 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AHPGDSORT1 | |
| SCHEMBL11582184 | 0.87 | MEN1 (0.59) | ALDH1A1MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL14112955 | 0.85 | HPGD (0.69) | ALDH1A1MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL4147334 | 0.85 | GPR27 (0.72) | ALDH1A1MEN1KMT2AHPGDTDP1 | |
| SCHEMBL12700350 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AHPGDSORT1 | |
| SCHEMBL6285639 | 0.83 | TMPRSS4 (0.67) | ALDH1A1MEN1KMT2AHPGDTDP1 | |
| SCHEMBL14514566 | 0.83 | PLG (0.67) | ALDH1A1MEN1KMT2AHPGDTDP1 | |
| SCHEMBL10489747 | 0.83 | NPC1 (0.60) | ALDH1A1MEN1KMT2AHPGDMAPK1 | |
| SCHEMBL14864556 | 0.83 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AHPGDMAPK1 | |
| SCHEMBL10489953 | 0.83 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2AHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070173498-A1 | Melanin concentrating hormone antagonist | KATO KANEYOSHI | 2007-07-26 | — | — | US | disclosed |
| US-7115750-B1 | Melanin concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173498-A1 | Melanin concentrating hormone antagonist | MC1R, MCHR1, MCHR2 | ALDH1A1 1784/4885MEN1 380/4885KMT2A 1886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.