SCHEMBL558324

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL559439	0.82	—	—
	SCHEMBL559438	0.82	ALDH1A1 (0.33)	ALDH1A1KDM4ECYP3A4MEN1KMT2A
	SCHEMBL558548	0.81	ALDH1A1 (0.40)	ALDH1A1KDM4EHSD17B10TSHR
	SCHEMBL558547	0.81	ALDH1A1 (0.39)	ALDH1A1KDM4ELMNAMAPTRAB9A
	SCHEMBL558137	0.76	ALDH1A1 (0.49)	ALDH1A1KDM4EHPGDCYP3A4MEN1
	SCHEMBL7449763	0.74	CLK4 (0.33)	—
	SCHEMBL7446479	0.72	MAPT (0.35)	ALDH1A1KDM4EHPGDMEN1KMT2A
	SCHEMBL4808825	0.72	ALDH1A1 (0.47)	ALDH1A1KDM4EHPGDCYP3A4HSD17B10
	SCHEMBL7450545	0.71	PTK2 (0.39)	ALDH1A1KDM4EHPGDCYP1A2CYP3A4
	SCHEMBL7107739	0.71	ECE1 (0.35)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.