Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.45 |
| ▸ | AXL | P30530 | 3/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583850 | 0.92 | KDR (0.50) | KDRNR1I2AXLPDGFRAFGFR2 | |
| SCHEMBL5584058 | 0.88 | NR1I2 (0.50) | KDRNR1I2TP53MAPTSMN1; SMN2 | |
| SCHEMBL5583578 | 0.86 | SMN1; SMN2 (0.53) | KDRNR1I2TP53MAPTSMN1; SMN2 | |
| SCHEMBL5583655 | 0.86 | RAB9A (0.53) | KDRAXLPDGFRAMETTP53 | |
| SCHEMBL5583759 | 0.86 | KDR (0.47) | KDRNR1I2AXLPDGFRAFGFR2 | |
| SCHEMBL4701462 | 0.85 | MAPT (0.52) | KDRMETMAPTRAF1 | |
| SCHEMBL2237038 | 0.84 | RAB9A (0.53) | KDRAXLPDGFRATP53MAPT | |
| SCHEMBL5583670 | 0.84 | KDR (0.55) | KDRAXLPDGFRAMETSMN1; SMN2 | |
| SCHEMBL5583862 | 0.84 | KDR (0.55) | KDRAXLMAPTRAF1 | |
| SCHEMBL14284622 | 0.83 | RAF1 (0.44) | KDRAXLPDGFRAMETRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |