Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 13/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583578 | 0.89 | SMN1; SMN2 (0.53) | NR1I2MAPTSMN1; SMN2TP53KDR | |
| SCHEMBL5583713 | 0.88 | KDR (0.46) | NR1I2MAPTSMN1; SMN2TP53KDR | |
| SCHEMBL5583560 | 0.86 | PKM (0.42) | NR1I2MAPTTSHRSMN1; SMN2TP53 | |
| SCHEMBL5583850 | 0.83 | KDR (0.50) | NR1I2MAPTSMN1; SMN2TP53KDR | |
| SCHEMBL5583704 | 0.82 | KDR (0.49) | MAPTTSHRSMN1; SMN2KDM4EKDR | |
| SCHEMBL5583719 | 0.80 | NPC1 (0.53) | MAPTSMN1; SMN2KDM4EALDH1A1KDR | |
| SCHEMBL5583675 | 0.80 | ALDH1A1 (0.48) | NR1I2MAPTTSHRSMN1; SMN2KDM4E | |
| SCHEMBL5583752 | 0.80 | MAPT (0.57) | MAPTKDR | |
| SCHEMBL5583759 | 0.80 | KDR (0.47) | NR1I2MAPTSMN1; SMN2TP53KDR | |
| SCHEMBL5583684 | 0.79 | KDM4E (0.55) | MAPTSMN1; SMN2KDM4EKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |