Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.60 |
| ▸ | RAB9A | P51151 | 10/20 | 0.60 |
| ▸ | TP53 | P04637 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583812 | 0.96 | NPC1 (0.64) | NPC1SMN1; SMN2RAB9ATP53ALDH1A1 | |
| SCHEMBL5583655 | 0.90 | RAB9A (0.53) | NPC1SMN1; SMN2RAB9ATP53ALDH1A1 | |
| SCHEMBL5583670 | 0.88 | KDR (0.55) | NPC1SMN1; SMN2RAB9AALDH1A1MAPK1 | |
| SCHEMBL2237038 | 0.88 | RAB9A (0.53) | NPC1SMN1; SMN2RAB9ATP53ALDH1A1 | |
| SCHEMBL5583593 | 0.87 | AXL (0.46) | NPC1SMN1; SMN2RAB9ATP53ALDH1A1 | |
| SCHEMBL14284595 | 0.87 | KDR (0.55) | RAB9AKDM4EKMT2AMEN1ALOX15 | |
| SCHEMBL14284581 | 0.86 | RAB9A (0.52) | NPC1SMN1; SMN2RAB9ATP53ALDH1A1 | |
| SCHEMBL5584055 | 0.85 | ABCC1 (0.53) | NPC1SMN1; SMN2RAB9APKMMAPT | |
| SCHEMBL5583850 | 0.85 | KDR (0.50) | SMN1; SMN2RAB9ATP53PKMMAPT | |
| SCHEMBL5583638 | 0.85 | AXL (0.44) | NPC1SMN1; SMN2RAB9ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |